We have added 5 new chimeric antibodies to study neuronal stress, Ca2+ dysregulation, and mitophagy in neurodegeneration
Our recombinant chimeric chicken and guinea pig antibodies are designed by pairing the proven specificity of the mouse monoclonal variable regions of our top selling antibodies with the constant region of chicken IgY or guinea pig IgG. By offering cleaner multiplexing and superior lot-to-lot consistency with reduced background noise, this animal-friendly hybrid format is the perfect solution for your demanding neuroscience research.
Learn more about recombinant antibodies!
New releases March 2026:
Anti-Ubiquitin Ser65 Phospho Antibody
Produced in collaboration with the Michael J Fox Foundation
Immunofluorescent staining for detection of phospho-Ubiquitin Ser65 in WT and PINK1-KO HeLa cells using our anti-phospho-Ubiquitin recombinant chicken monoclonal antibody [30H3K1] (Cat No. 78-605). Cells were treated with 20 µM carbonyl 3-chlorophenylhydrazone (CCCP) for 4 h, then fixed by adding 4% paraformaldehyde for 10 min. The anti-phospho-Ubiquitin Ser65 antibody (Cat. 78-605) was added in a solution of 1% BSA in PBS for 60 min at a concentration of 1 μg/mL. See full details in the image on the product page. Images courtesy of Wolfdieter Springer and Fabienne Fiesel, Mayo Clinic, Jacksonville, Florida.
Four more chimeric versions of some of our most popular NeuroMabs:
Anti-CSPG4/NG2 Antibody
Immunohistochemistry for detection of CSPG4/NG2 in adult rat hippocampus using our anti-CSPG4/NG2 recombinant chicken monoclonal antibody (Cat No. 78-523). Derived from NeuroMab clone 6203-34, it detects human, mouse, and rat CSPG4/NG2 and is purified by affinity chromatography. It works in ELISA, ICC, IHC, WB.
Anti-TMEM240 Antibody
Immunohistochemistry for detection of TMEM240 in adult rat hippocampus using our anti-TMEM240 recombinant chicken monoclonal antibody (Cat No. 78-533). Derived from NeuroMab clone N498/28, it detects human, mouse, and rat TMEM240 and works in ELISA, ICC, IHC, WB.
Anti-Ryanodine Receptor Type 2 (RyR2) Antibody
Immunohistochemistry for detection of Ryanodine Receptor (RyR2) in adult rat hippocampus using our anti-RyR2 recombinant chicken monoclonal antibody (Cat No. 78-534). Derived from NeuroMab clone N501/49, it detects human, mouse, and rat RyR2 and is purified by affinity chromatography. It works in ELISA, ICC, IHC, WB.
Anti-Cav1.2 Ca2+ Channel Antibody
Immunohistochemistry for detection of Cav1.2 calcium channel in adult rat cerebellum using our anti-Cav1.2 recombinant chicken monoclonal antibody (Cat No. 78-535). Derived from NeuroMab clone N500/4, it detects human, mouse, and rat Cav1.2 and is purified by affinity chromatography. It works in ELISA, ICC, IHC, WB.
For the 4 NeuroMab chimeric antibodies above:
Tissue was fixed with 4% paraformaldehyde and paraffin embedded. Heat induced antigen retrieval was performed using citrate buffer (Cat No. AR-6544) and then blocked with Immuno Protein Blocking Solution with Goat Serum (Cat No. AR-6591). The primary antibody was incubated with the sample at a dilution of 1:250 at 4C overnight. After washing with PBST, the sections were stained using goat anti-chicken IgY CF488 secondary antibody (Cat No. 80-1001-488) (green). DAPI nuclear stain (blue) shows cell nuclei.
Check out our other chicken recombinant antibodies :
CALB1/Calbindin Calretinin GFAP Parvalbumin TMEM119
PSD-95 VGlut1 VGlut2 VGAT Homer1 Bassoon GAD65/67
Ankyrin-G LRRK2/Dardarin, CT Arl13b Beta-4 Spectrin TH
Nav1.1 Na+ Channel GluN2B/NR2B RGS14 Olig1 VAChT c-FOS
Pink1 Human Serum Albumin Cortactin Cytokeratin 8 M6PR Rab 9