Adenovirus Citations

Hundreds of scientists use our adenoviruses to further their research!


Featured Citations

Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice.

Yu L, et al. Nature Communications. 2023 Jul 25;14(1):4101. PMID: 37491347

FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress.

Kobiita A, Cell Reports. 2023 Aug 29;42(8):112986. PMID: 37590136

Citations By Research Area

Expand each research area to view detailed citations.


PMID Publication
27468832 Chen Y, et al. 2016. Bone morphogenetic protein 2 stimulates chondrogenesis of equine synovial membrane-derived progenitor cells. Veterinary and Comparative Orthopaedics and Traumatology, 378-385.
26414599 Lipner Justin, et al. 2015. In Vivo Evaluation of Adipose-Derived Stromal Cells Delivered with a Nanofiber Scaffold for Tendon-to-Bone Repair. Tissue Engineering. Part A, 2766-2774.
PMID Publication
32647171 M Arra, et al. 2020. LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis. Nature Communications, 3427.
PMID Publication
29310783 Kirby, D.J., et al. 2018. Isolation, production, and analysis of small leucine-rich proteoglycans in bone. Methods in Cell Biology, 281-296.
27734388 Maeda A, et al. 2017. Analysis of CCN4 Function in Osteogenic and Osteoclastic Cells Using Gain and Loss of Function Approaches. Methods of Molecular Biology, 347-359.
23686246 Zhang Y, et al. 2013. Ubiquitin-like domain of IKKβ regulates osteoclastogenesis and osteolysis. Calcified Tissue International, 78-85.
PMID Publication
22333182 Auld KL, et al. 2012. Estrogen-related receptor α regulates osteoblast differentiation via Wnt/β-catenin signaling. Journal of Molecular Biology, 177-191.


PMID Publication
36192379 AP Amini, et al. 2022. Multiscale profiling of protease activity in cancer. Nature Communications, 5745.
30405106 Title, A.C., et al. 2018. Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion. Nature Communications, 4671.
29848755 J Alagu, et al. 2018. Tumor Suppressor p14ARF Enhances IFN-γ-Activated Immune Response by Inhibiting PIAS1 via SUMOylation. Journal of Immunology, 451-464.
Bladder Cancer
PMID Publication
34938855 JL Green, et al. 2021. Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance. MolecularTherapy Oncolytics, 547-559.
Bone Cancer
PMID Publication
30422869 CK Appel, et al. 2019. Decitabine attenuates nociceptive behavior in a murine model of bone cancer pain. Pain, 619-631.
Breast Cancer
PMID Publication
25965299 Okoh VO, et al. 2015. Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells. British Journal of Cancer, 1687-1702.
23437041 Okoh VO, et al. 2013. Reactive oxygen species via redox signaling to PI3K/AKT pathway contribute to the malignant growth of 4-hydroxy estradiol-transformed mammary epithelial cells. PLoS One, e54206.
15746050 Dwyer RM, et al. 2005. In vivo radioiodide imaging and treatment of breast cancer xenografts after MUC1-driven expression of the sodium iodide symporter. Clinical Cancer Research, 1483-1489.
Colorectal Cancer
PMID Publication
31239267 C Tacconi, et al. 2019. Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer. Cancer Research, 4196-4210.
28886484 Brandt, K.E., et al. 2018. Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biology, 82-87.
25754161 Tacconi C, et al. 2015. Vascular endothelial growth factor C disrupts the endothelial lymphatic barrier to promote colorectal cancer invasion. Gastroenterology, 1438-1451.
15510175 Scholz IV, et al. 2005. Radioiodine therapy of colon cancer following tissue-specific sodium iodide symporter gene transfer. Gene Therapy, 272-280.
Cancer Drug Therapy
PMID Publication
35262628 H Jiang, et al. 2022. Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors. Journal of Experimental Medicine, .
28389407 Sciegienka, S.J., et al. 2017. D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H2O2-mediated oxidative stress. Free Radical Biology and Medicine, 354-361.
Epithelial Cancer
PMID Publication
27849011 Wang Y, et al. 2016. Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis. Scientific Reports, 37213.
PMID Publication
29755109 Barrett, J.A., et al. 2018. Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System® (RTS®) gene switch as gene therapy for the treatment of glioma. Cancer Gene Therapy, 106-116.
28695888 Cook PJ, et al. 2017. Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target. Nature Communications, 15987.
Cancer Immunotherapy Treatment
PMID Publication
33335088 AJ Wisdom, et al. 2020. Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy. Nature Communications, 6410.
26374823 Gabitzsch ES, et al. 2015. The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic. Oncotarget, 31344-31359.
22737604 Blalock LT, et al. 2012. Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity. Oncoimmunology, 287-357.
Liver Cancer
PMID Publication
26204498 De la Rosa ÁJ, et al. 2016. Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma. Gene Therapy, 67-77.
Lung Cancer
PMID Publication
38626916 Horvat, N.K., et al. 2024. Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce Lung Cancer Regrowth after Crizotinib Treatment. ACS Nano, .
37161053 Berr AL, et al. 2023. Vimentin is required for tumor progression and metastasis in a mouse model of non–small cell lung cancer. Oncogene, 2074-2087.
36739466 EK Kleczko, et al. 2023. Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity. NPJ Precision Oncology, 15.
36538983 Yang J, et al. 2023. Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10. Cancer Letters, 216025.
36192757 N Merle, et al. 2022. Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase. Molecular Cancer, 191.
36175034 S Naranjo, et al. 2022. Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform. Genes Development, 936-949.
36112789 A Vaishnavi, et al. 2022. Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis. Cancer Research, 4261-4273.
32874131 K Nolan, et al. 2020. Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models. Cancer Cell International, 417.
29118090 Kwak, J.W., et al. 2018. Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression. Cancer Research, 143-156.
26567140 Green S, et al. 2015. PIK3CA(H1047R) Accelerates and Enhances KRAS(G12D)-Driven Lung Tumorigenesis. Cancer Research, 5378-5391.
26001956 Shai A, et al. 2015. TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis. Cancer Research, 3167-3180.
24589553 Juan J, et al. 2014. Diminished WNT -> β-catenin -> c-MYC signaling is a barrier for malignant progression of BRAFV600E-induced lung tumors. Genes Development, 561-575.
24292713 Glasauer A, et al. 2014. Targeting SOD1 reduces experimental non–small-cell lung cancer. Journal of Clinical Investigation, 117-128.
24019382 Trejo CL, et al. 2013. Mutationally activated PIK3CA(H1047R) cooperates with BRAF(V600E) to promote lung cancer progression. Cancer Research, 6448-6461.
22511580 Trejo CL, et al. 2012. MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E. Cancer Research, 3048-3059.
22321727 Rehman J, et al. 2012. Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer. FASEB Journal, 2175-2186.
PMID Publication
33378390 KC Kloepping, et al. 2020. Triphenylphosphonium derivatives disrupt metabolism and inhibit melanoma growth in vivo when delivered via a thermosensitive hydrogel. PLoS One, e0244540.
PMID Publication
23448979 Carotenuto M, et al. 2013. Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction. Scientific Reports, 1351.
Opioid Use for Cancer Pain
PMID Publication
28456745 Viet CT, et al. 2017. OPRM1 Methylation Contributes to Opioid Tolerance in Cancer Patients. The Journal of Pain, 1046-1059.
Oral Cancer
PMID Publication
33257729 D Dang, et al. 2020. Targeting the endothelin axis as a therapeutic strategy for oral cancer metastasis and pain. Scientific Reports, 20832.
24963050 Viet CT, et al. 2014. Demethylating drugs as novel analgesics for cancer pain. Clinical Cancer Research, 4882-4893.
Pancreatic Cancer
PMID Publication
33404013 JT Polaski, et al. 2021. The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma. Elife, e62209.
24509158 Sibenaller ZA, et al. 2014. Extracellular superoxide dismutase suppresses hypoxia-inducible factor-1α in pancreatic cancer. Free Radical Biology and Medicine, 357-366.
Prostate Cancer
PMID Publication
30009471 Li, D., et al. 2018. Inhibition of androgen receptor transactivation function by adenovirus type 12 E1A undermines prostate cancer cell survival. Prostate, 140-1156.
29421238 Zhong, W., et al. 2018. Extracellular redox state shift: A novel approach to target prostate cancer invasion. Free Radical Biology and Medicine, 99-109.
28108513 Xiaowei Wei, et al. 2017. RelB Expression Determines the Differential Effects of Ascorbic Acid in Normal and Cancer Cells. Cancer Research, 1345-1356.
27671770 Tong Q, et al. 2016. MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell. Free Radical Biology and Medicine, 32-43.
24369144 Gao XF, et al. 2014. Radioiodine therapy for castration-resistant prostate cancer following prostate-specific membrane antigen promoter-mediated transfer of the human sodium iodide symporter. Asian Journal of Andrology, 120-123.
Cancer Radiation Therapy and Effects
PMID Publication
36462795 G Gonon, et al. 2022. Impact of the redox environment on propagation of radiation bystander effects: The modulating effect of oxidative metabolism and oxygen partial pressure. Mutation Research. Genetic Toxiocoly and Environmental Mutagenesis, .
36162051 Patel R, et al. 2023. Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma. Molecular Cancer Therapies, 112-122.
35767986 Nadkarni R, et al. 2022. Material decomposition from photon-counting CT using a convolutional neural network and energy-integrating CT training labels. Physics in Medicine and Biology, .
35314638 AJ Allphin, et al. 2022. Photon Counting CT and Radiomic Analysis Enables Differentiation of Tumors Based on Lymphocyte Burden. Tomography, 740-753.
35100573 Johnson TR, et al. 2022. An investigation of kV mini-GRID spatially fractionated radiation therapy: dosimetry and preclinical trial. Physics in Medicine and Biology, .
32718998 RD Dodd, et al. 2020. Tumor Subtype Determines Therapeutic Response to Chimeric Polypeptide Nanoparticle-based Chemotherapy in Pten-deleted Mouse Models of Sarcoma. Clinical Cancer Research, 5036-5047.
32032663 KC Falls-Hubert, et al. 2020. Disulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper. Free Radical Biology and Medicine, 45302.
31427882 M Chen, et al. 2019. The Fusion Oncogene FUS-CHOP Drives Sarcomagenesis of High-Grade Spindle Cell Sarcomas in Mice. Sarcoma, 1340261.
24193032 Grünwald GK, et al. 2013. EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene. Molecular Therapy. Nucleic Acids, e131.
23936314 Stancevic B, et al. 2013. Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure. PLoS One, e69025.
23843567 Grünwald GK, et al. 2013. Systemic image-guided liver cancer radiovirotherapy using dendrimer-coated adenovirus encoding the sodium iodide symporter as theranostic gene. Journal of Nuclear Medicine, 1450-1457.
23038026 Grünwald GK, et al. 2013. Sodium iodide symporter (NIS)-mediated radiovirotherapy of hepatocellular cancer using a conditionally replicating adenovirus. Gene Therapy, 625-633.
Cancer Resonance Imaging
PMID Publication
37721686 AG Rickard, et al. 2023. Evaluating Tumor Hypoxia Radiosensitization Via Electron Paramagnetic Resonance Oxygen Imaging (EPROI). Molecular Imaging and Biology, .
Super Oxide
PMID Publication
36935009 SS Sabharwal, et al. 2023. H2O2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo. Journal of Biological Chemistry, 104624.
36581766 J Du, et al. 2022. The role of mitochondria in pharmacological ascorbate-induced toxicity. Scientific Reports, 22521.
33980575 BJ Sishc, et al. 2021. Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide. Science Translational Medicine, eabb3768.
32512786 Y Zhu, et al. 2020. MnTE-2-PyP Suppresses Prostate Cancer Cell Growth via H2O2 Production. Antioxidants, 490.
22392697 Du J, et al. 2013. Regulation of pancreatic cancer growth by superoxide. Molecular Carcinogenesis, 555-567.
Thyroid Cancer
PMID Publication
17931047 Spitzweg C, et al. 2007. Image-guided radioiodide therapy of medullary thyroid cancer after carcinoembryonic antigen promoter-targeted sodium iodide symporter gene expression. Human Gene Therapy, 916-924.
Viruses related to Cancer
PMID Publication
22241994 Olmstead AD, et al. 2012. Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents. PLoS Pathology, e1002468.
26337747 Rice AE, et al. 2015. An HPV-E6/E7 immunotherapy plus PD-1 checkpoint inhibition results in tumor regression and reduction in PD-L1 expression. Cancer Gene Therapy, 454-462.


PMID Publication
38309417 Wang Y, et al. 2024. Geranylgeranyl isoprenoids and hepatic Rap1a regulate basal and statin-induced expression of PCSK9. Journal of Lipid Research, 100515.
28882874 Loregger A1, et al. 2017. Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis. Arteriosclerosis, Thrombosis, and Vascular Biology, 2064-2074.
28231341 Cook EC, et al. 2017. Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene. PLoS One, e0172721.
27551042 Caceres PS, et al. 2016. Vesicle-associated Membrane Protein 3 (VAMP3) Mediates Constitutive Trafficking of the Renal Co-transporter NKCC2 in Thick Ascending Limbs: ROLE IN RENAL FUNCTION AND BLOOD PRESSURE. Journal of Biological Chemistry, 22063-22073.
27528004 Ang R, et al. 2015. The role of GαO-mediated signaling in the rostral ventrolateral medulla oblongata in cardiovascular reflexes and control of cardiac ventricular excitability. Physiological Reports, e12860.
27251289 Tamer Sallam, et al. 2016. Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature, 124-128.
26098115 Kelloniemi A, et al. 2015. The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression. PLoS One, .
24363997 Li S, et al. 2014. Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide. Redox Biology, 8-14.
23269646 Mendez M, et al. 2013. Role of the SNARE protein SNAP23 on cAMP-stimulated renin release in mouse juxtaglomerular cells. American Journal of Physiology. Renal Physiology, F498-504.
22437887 Gebhard C, et al. 2012. Caffeine induces endothelial tissue factor expression via phosphatidylinositol 3-kinase inhibition. Thrombosis and Haemostasis, 884-894.
PMID Publication
28011587 Joseph G, et al. 2017. Elevated 20-HETE impairs coronary collateral growth in metabolic syndrome via endothelial dysfunction. American Journal of Physiology. Heart and Circulatory Physiology, H528-H540.
PMID Publication
31865373 KB Collins, et al. 2019. Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis. Journal of Cellular Biology, .
PMID Publication
37491347 L Yu, et al. 2023. Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice. Nature Communications, 4101.
34551209 IF Hall, et al. 2021. rs41291957 controls miR-143 and miR-145 expression and impacts coronary artery disease risk. EMBO Molecular Medicine, e14060.
28972541 Doran AC, et al. 2017. CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. Journal of Clinical Investigation, 4075-4089.
24469459 Blackstock CD, et al. 2014. Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA. Journal of Biological Chemistry, 7264-7274.
23912991 Jiang XC, et al. 2013. Generation of general and tissue-specific gene knockout mouse models. Methods of Molecular Biology, 253-271.
Cardiac Hypertrophy
PMID Publication
29128355 Romano, N., et al. 2018. Upregulation of eIF6 inhibits cardiac hypertrophy induced by phenylephrine. Biochemical and Biophysical Research Communications, 601-606.
PMID Publication
37499888 Y Chen, et al. 2023. Ferroptosis contributes to catecholamine-induced cardiotoxicity and pathological remodeling. Free Radical Biology and Medicine, 227-238.
Cardiovascular Disease
PMID Publication
29558369 Elia, L., et al. 2018. UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease. Journal of Clinical Investigation, 2473-2486.
PMID Publication
33539326 RB Kasetti, et al. 2021. Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin. JCI Insight, e143359.
Heart Failure
PMID Publication
27297082 Collister JP, et al. 2016. Overexpression of copper/zinc superoxide dismutase in the median preoptic nucleus improves cardiac function after myocardial infarction in the rat. Clinical and Experimental Pharmacology and Physiology, 960-966.
PMID Publication
28910144 Budas GR, et al. 2017. ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 373-385.
26881025 John P. Collister, et al. 2016. Angiotensin II-Induced Hypertension Is Attenuated by Overexpressing Copper/Zinc Superoxide Dismutase in the Brain Organum Vasculosum of the Lamina Terminalis. Oxidative Medicine and Cellular Longevity, 3959087.
25474089 Collister JP, et al. 2014. Over-expression of copper/zinc superoxide dismutase in the median preoptic nucleus attenuates chronic angiotensin II-induced hypertension in the rat. Internation Journal of Molecular Science, 22203-22213.
25008321 Caceres PS, et al. 2014. Vesicle-associated membrane protein 2 (VAMP2) but Not VAMP3 mediates cAMP-stimulated trafficking of the renal Na+-K+-2Cl- co-transporter NKCC2 in thick ascending limbs. Journal of Biological Chemistry, 23951-62.
24618552 Tsang H, et al. 2013. Role of asymmetric methylarginine and connexin 43 in the regulation of pulmonary endothelial function. Pulmonary Circulation, 675-691.
Microvascular Lesions
PMID Publication
27813591 Dong W, et al. 2016. Preliminary in vitro analysis of mechanism of cardiac microvascular endothelial barrier function. Genetics and Molecular Research, .
25090023 Das JK, et al. 2014. PCB153-induced overexpression of ID3 contributes to the development of microvascular lesions. PLoS One, e104159.
Noonan Syndrome
PMID Publication
37450595 Cuevas-Navarro A, et al. 2023. RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome–associated cardiac hypertrophy. Science Advances, eadf4766.

Cell Biology

Cell Biology
PMID Publication
37726294 Y Chen, et al. 2023. Oxidative stress induces mitochondrial iron overload and ferroptotic cell death. Scientific Reports, 15515.
37590136 A Kobiita, et al. 2023. FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress. Cell Reports, 112986.
36401888 M Waldeck-Weiermair, et al. 2022. Differential endothelial hydrogen peroxide signaling via Nox isoforms: Critical roles for Rac1 and modulation by statins. Redox Biology, 102539.
35262628 H Jiang, et al. 2022. Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors. Journal of Experimental Medicine, .
35002214 S Gindina, et al. 2021. Tissue plasminogen activator rescues steroid-induced outflow facility reduction via non-enzymatic action. Molecular Vision, 691-705.
34774525 Y Chiang, et al. 2021. Sphingomyelin synthases 1 and 2 exhibit phosphatidylcholine phospholipase C activity. Journal of Biological Chemistry, 101398.
34332077 Y Chiang, et al. 2021. Sphingomyelin synthase related protein is a mammalian phosphatidylethanolamine phospholipase C. Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, 159017.
34230483 H Torres-Torrelo, et al. 2021. Lactate sensing mechanisms in arterial chemoreceptor cells. Nature Communications, 4166.
34027492 L Gao, et al. 2021. Using redox-sensitive fluorescent probes to record real-time reactive oxygen species production in cells from mouse carotid body slices. STAR Protocols, 100535.
33154371 RB Kasetti, et al. 2020. ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load. Nature Communications, 5594.
32438526 J Kersigo, et al. 2021. Effects of Neurod1 Expression on Mouse and Human Schwannoma Cells. Laryngoscope, E259-E270.
31537645 MC de Miranda, et al. 2019. Epidermal growth factor (EGF) triggers nuclear calcium signaling through the intranuclear phospholipase Cδ-4 (PLCδ4). Journal of Biological Chemistry, 16650-16662.
30415700 Rodriguez-Rodriguez, J.A., et al. 2018. Distinct roles of RZZ and Bub1-KNL1 in mitotic checkpoint signaling and kinetochore expansion. Current Biology, 3422-3429.
30087458 Jung, M., et al. 2018. Lipocalin-2 abrogates epithelial cell cycle arrest by PPARγ inhibition. Lab Investigation, 1408-1422.
30003094 Freundt, J.K., et al. 2018. The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation. BioMed Research Institute, 3694362.
28003364 Leech CA, et al. 2017. Stromal Interaction Molecule 1 (STIM1) Regulates ATP-sensitive Potassium (KATP) and Store-operated Ca2+ Channels in MIN6 β-Cells. Journal of Biological Chemistry, 2266-2277.
27753532 Paul PK, et al. 2016. Histone chaperone ASF1B promotes human β-cell proliferation via recruitment of histone H3.3. Cell Cycle, 3191-3202.
27744291 Gay O, et al. 2016. Refilins are short-lived Actin-bundling proteins that regulate lamellipodium protrusion dynamics. Biology Open, 1351-1361.
27620490 Yun B, et al. 2016. Off-target effect of the cPLA2α inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulum. Biochemical and Biophysical Research Communications, 61-66.
27470512 Song SH, et al. 2016. Fibroblast Growth Factor 12 Is a Novel Regulator of Vascular Smooth Muscle Cell Plasticity and Fate. Arteriosclerosis, Thrombosis, and Vascular Biology, 1928-1936.
27142834 Tokhtaeva E, et al. 2016. The O-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell-cell trans-dimerization of Na,K-ATPase β1 subunits. Journal of Cell Science, 2394-2406.
26538436 AB Jaykumar, et al. 2016. Real-time monitoring of NKCC2 endocytosis by total internal reflection fluorescence (TIRF) microscopy. American Journal of Physiology. Renal Physiology, F183-F191.
26429917 Krisenko MO, et al. 2015. Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy. Journal of Biological Chemistry, 27803-27815.
25806685 Rong X, et al. 2015. Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion. Elife, e06557.
24506535 Wang Y, et al. 2014. Uncoupling of Cav1.2 from Ca(2+)-induced Ca(2+) release and SK channel regulation in pancreatic β-cells. Molecular Endocrinology, 458-476.
24109596 Neto H, et al. 2013. Syntaxin 16 is a master recruitment factor for cytokinesis. Molecular Biology of the Cell, 3663-3674.
23419260 Zhang L, et al. 2013. Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor. Journal of Lipid Research, 1410-1420.
22422475 In JG, et al. 2012. Analysis of polarized membrane traffic in hepatocytes and hepatic cell lines. Current Protocols in Cell Biology, .
22262167 Yang H, et al. 2012. Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection. Cell Cycle, 582-593.
22041456 Owens, K.M., et al. 2012. Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2(-•) and H2O2. Free Radical Biology and Medicine, 160-166.
36012732 J Woo, et al. 2022. Hair Growth Regulation by Fibroblast Growth Factor 12 (FGF12). International Journal of Molecular Science, 9467.
32278283 JM Stolwijk, et al. 2020. Simultaneous detection of the enzyme activities of GPx1 and GPx4 guide optimization of selenium in cell biological experiments. Redox Biology, 101518.
32396862 D Guallar, et al. 2020. ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress. Cell Stem Cell, 300-314.
24598361 Koppel AC, et al. 2014. Delayed skin wound repair in proline-rich protein tyrosine kinase 2 knockout mice. American Journal of Physiology. Cell Physiology, C899-C909.
32628158 AT Aliyev, et al. 2020. Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein. Journal of Visualized Experiments, .


PMID Publication
38203312 J Hwang, et al. 2023. A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving β-AR Agonism and Cofilin. International Journal of Molecular Medicine, 137.
37759961 R Balakrishnan, et al. 2023. Toward Ameliorating Insulin Resistance: Targeting a Novel PAK1 Signaling Pathway Required for Skeletal Muscle Mitochondrial Function. Antioxidants, 1658.
37294632 A Pelligra, et al. 2023. Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism. Cell Reports, 112615.
36543979 K Griess, et al. 2023. Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis. Nature Cell Biology, 20-29.
36446811 AM Koester, et al. 2022. GLUT4 translocation and dispersal operate in multiple cell types and are negatively correlated with cell size in adipocytes. Scientific Reports, 20535.
36001955 Y Wang, et al. 2022. Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia. Cell Reports, 111259.
35377441 Chatterjee Bhowmick D, et al. 2022. DOC2b enhances β-cell function via a novel tyrosine phosphorylation-dependent mechanism. Diabetes, 1246-1260.
35222279 KE Merz, et al. 2022. Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis. Frontiers in Endocrinology, 821849.
34371064 K Meneyrol, et al. 2021. Ovarian insufficiency impairs glucose-stimulated insulin secretion through activation of hypothalamic de novo ceramide synthesis. Metabolism, 154846.
34303021 W Dai, et al. 2021. Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance. Molecular Metabolism, 101300.
34116231 AC Title, et al. 2021. The miR-200-Zeb1 axis regulates key aspects of β-cell function and survival in vivo. Molecular Metabolism, 101267.
33172888 MD Schaid, et al. 2021. Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes. Journal of Biological Chemistry, 100056.
32640216 A Kobiita, et al. 2020. The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress. Cell Reports, 107846.
32341128 B Yau, et al. 2020. A fluorescent timer reporter enables sorting of insulin secretory granules by age. Journal of Biological Chemistry, 8901-8911.
30707251 J Zhang, et al. 2019. DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle. Diabetologia, 845-859.
30305365 Oh, E., et al. 2018. Syntaxin 4 expression in pancreatic β-cells promotes islet function and protects functional β-cell mass. Diabetes, 2626-2639.
30131394 Kono, T., et al. 2018. Impaired store-operated calcium entry and STIM1 loss lead to reduced insulin secretion and increased endoplasmic reticulum stress in the diabetic β-cell. Diabetes, 2293-2304.
29661782 Arianne Aslamy, et al. 2018. Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function. Diabetes, 1332-1344.
29491394 Chepurny, O.G., et al. 2018. Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors. Scientific Reports, 3749.
27394663 Ahn M, et al. 2016. The p21-activated kinase (PAK1) is involved in diet-induced beta cell mass expansion and survival in mice and human islets. Diabetologia, 2145-2155.
27007848 Stanley, S.A., et al. 2016. Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism. Nature, 647-650.
26394663 Lavine JA, et al. 2015. Cholecystokinin expression in the β-cell leads to increased β-cell area in aged mice and protects from streptozotocin-induced diabetes and apoptosis. American Journal of Physiology. Endrocrinology and Metabolism, E819-E828.
26348837 Kluth O, et al. 2015. Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation. PLoS Genetics, e1005506.
25985365 Belgardt BF, et al. 2015. The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes. Nature Medicine, 619-627.
25295789 Raichur S, et al. 2014. CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. Cell Metabolism, 687-695.
24732803 Kawano Y, et al. 2014. Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization. Molecular and Cellular Biology, 2396-2408.
24610809 Yoder SM, et al. 2014. YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cells. Journal of Biological Chemistry, 11476-11487.
24466075 van Stijn CM, et al. 2014. Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis. PLoS One, e86404.
24424049 Neumann UH, et al. 2014. IGFBP2 is neither sufficient nor necessary for the physiological actions of leptin on glucose homeostasis in male ob/ob mice. Endocrinology, 716-725.
22888137 Huber AK, et al. 2012. Genetically driven target tissue overexpression of CD40: a novel mechanism in autoimmune disease. Journal of Immunology, 3043-3053.
22394502 Hall AM, et al. 2012. Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. Journal of Lipid Research, 990-999.
22108804 Kalwat MA, et al. 2012. Gelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis. Molecular Endocrinology, 128-141.
15538371 Poy MN, et al. 2004. A pancreatic islet-specific microRNA regulates insulin secretion. Nature, 226-230.
PMID Publication
30582457 S Spolitu, et al. 2019. Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol. Circulation, 38-51.
PMID Publication
31597092 KC Nikolaou, et al. 2019. The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing. Cell Reports, 283-300.
28714135 Hu Y, et al. 2017. YAP suppresses gluconeogenic gene expression through PGC1α. Hepatology, 2029-2041.
Insulin Resistance
PMID Publication
30523156 V Tillander, et al. 2019. Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1-induced steatosis. Journal of Biological Chemistry, 2009-2020.
23832089 Pajvani UB, et al. 2013. Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability. Nature Medicine, 1054-1060.
22474127 Hu S, et al. 2012. Peroxisome proliferator-activated receptor γ decouples fatty acid uptake from lipid inhibition of insulin signaling in skeletal muscle. Molecular Endocrinology, 977-988.
Kidney Disease
PMID Publication
30407737 R Guiteras, et al. 2019. Exploring macrophage cell therapy on Diabetic Kidney Disease. Journal Cellular and Molecular Medicine, 841-851.
Trim-Away/ Liver Disease
PMID Publication
37937648 KC Nikolaou, et al. 2023. Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators. JCI Insight, e164694.
Non-Alcoholic Fatty Liver Disease
PMID Publication
24362075 Castaño D, et al. 2014. Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation. Journal of Hepatology, 1017-1025.
PMID Publication
33449689 BT Milliken, et al. 2021. Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis. Journal of Medicinal Chemistry, 1127-1138.
33352310 B Chaurasia, et al. 2021. Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes. Molecular Metabolism, 101145.
27110486 Okada, K., et al. 2016. Thioesterase superfamily member 1 suppresses cold thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids in brown adipose tissue. Molecular Metabolism, 340-351.
26909312 Quiñones M, et al. 2015. Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance. Molecular Metabolism, 961-970.

Fatty Acids

Fatty Acids
PMID Publication
30223548 Alam, S., et al. 2018. PCB11 Metabolite, 3, 3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3 …. Antioxidants, 121.
29317465 Lin, J., et al. 2018. Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells [S]. Journal of Lipid Research, 46-428.
PMID Publication
34108467 Y Li, et al. 2021. Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice. Nature Communications, 3493.
PMID Publication
31227231 EA Lane, et al. 2019. HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP. Molecular Cell, 357-371.


PMID Publication
32977155 IG Luzina, et al. 2020. Full-length IL-33 regulates Smad3 phosphorylation and gene transcription in a distinctive AP2-dependent manner. Cell Immunology, 104203.
28793288 Guiteras R, et al. 2017. Macrophage Overexpressing NGAL Ameliorated Kidney Fibrosis in the UUO Mice Model. Cellular Physiology and Biochemistry, 1945-1960.
26993524 Luzina IG, et al. 2016. Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology, L940-L954.
25786688 Hashimoto M1, et al. 2015. A critical role for dendritic cells in the evolution of IL-1β-mediated murine airway disease. Journal of Immunology, 3962-3969.
25188360 Morales-Nebreda LI, et al. 2015. Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology, 503-512.
PMID Publication
30504459 Z Zheng, et al. 2019. An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. Blood, 743-753.

Gene Editing / Expression, CRISPR/Cas9

PMID Publication
37684258 QR Brockman, et al. 2023. Discrepancies in indel software resolution with somatic CRISPR/Cas9 tumorigenesis models. Scientific Reports, 14798.
37470475 L Schubert, et al. 2023. A functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes. Biology Open, bio059994.
34099655 A Goga, et al. 2021. miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine. Nature Communications, 3339.
32456131 A Scherer, et al. 2020. Distinct Tumor Microenvironments Are a Defining Feature of Strain-Specific CRISPR/Cas9-Induced MPNSTs. Genes, 583.
31209054 J Lee, et al. 2019. Direct delivery of adenoviral CRISPR/Cas9 vector into the blastoderm for generation of targeted gene knockout in quail. PNAS: USA, 13288-13292.
28691711 Huang J, et al. 2017. Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma. Nature Communications, 15999.
26086867 Wang D, et al. 2015. Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses. Human Gene Therapy, 432-42.
25337876 Maddalo D, et al. 2014. In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system. Nature, 423-427.

Hyperoxia / Hypoxia

PMID Publication
34596045 A Kumar, et al. 2021. HIF1α stabilization in hypoxia is not oxidant-initiated. Elife, e72873.
31848220 A Moreno-Domínguez, et al. 2020. Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors. Sicence Signaling , 615.
29887397 Arias-Mayenco, I., et al. 2018. Acute O2 Sensing: Role of Coenzyme QH2/Q Ratio and Mitochondrial ROS Compartmentalization. Cell Metabolism, 145-158.
22229392 Farrow KN, et al. 2012. Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells. Antioxidants and Redox Signaling, 460-470.
Oxidative Stress
PMID Publication
25416362 Alim I, et al. 2014. Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells. Methods of Enzymology, 251-273.
PMID Publication
32590330 SSS Saravi, et al. 2020. Differential endothelial signaling responses elicited by chemogenetic H2O2 synthesis. Redox Biology, 101605.
Metabolic Side-Effects
PMID Publication
32733884 T Eberhart, et al. 2020. Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression. Frontiers in Cell and Developmental Biology, 566.


PMID Publication
22294347 Varela L, et al. 2012. Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism. Journal of Pathology, 209-222.
Graves Disease
PMID Publication
35881515 K Merakchi, et al. 2022. Murine Thyroid IL-4 Expression Worsens Hypothyroidism on Iodine Restriction and Mitigates Graves Disease Development. Endocrinology, .
32228171 LC Faustino, et al. 2020. A Novel Mouse Model of Autoimmune Thyroiditis Induced by Immunization with Adenovirus Containing Full-Length Thyroglobulin cDNA: Implications to Genetic Studies of Thyroid Autoimmunity. Thyroid, 1338-1345.
31980336 CW Li, et al. 2020. Cepharanthine blocks TSH receptor peptide presentation by HLA-DR3: Therapeutic implications to Graves' disease. Journal of Autoimmunity, 102402.
25051451 McLachlan SM, et al. 2014. Immunoglobulin heavy chain variable region and major histocompatibility region genes are linked to induced graves' disease in females from two very large families of recombinant inbred mice. Endocrinology, 4094-4103.


PMID Publication
31468569 LI Labzin, et al. 2019. Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection. EMBO Journal, e101365.
30856600 IG Luzina, et al. 2019. Identification of the IL-33 protein segment that controls subcellular localization, extracellular secretion, and functional maturation. Cytokine, 1-6.
30115681 De, S., et al. 2018. Mechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signaling. Journal of Biological Chemistry, 15208-15220.
29249357 Rajbhandari, P., et al. 2018. IL-10 signaling remodels adipose chromatin architecture to limit thermogenesis and energy expenditure. Cell, 218-233.
28732035 Martins MA, et al. 2017. Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques. PLoS Pathology, e1006529.
27881870 Bottermann, M., et al. 2016. Antibody-antigen kinetics constrain intracellular humoral immunity. Scientific Reports, 37457.
PMID Publication
34398520 P Seoane‐Collazo, et al. 2022. Activation of Hypothalamic AMP-Activated Protein Kinase Ameliorates Metabolic Complications of Experimental Arthritis. Arthritis and Rheumatology, 212-222.
PMID Publication
25686493 Boaru SG, et al. 2015. NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes. Biochemical and Biophysical Research Communications, 700-706.
25349202 Jung YJ, et al. 2014. SIRT2 Regulates LPS-Induced Renal Tubular CXCL2 and CCL2 Expression. Journal of American Society of Nephrology, 1549-1560.
24619410 Kopach P, et al. 2014. IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism. Journal of Biological Chemistry, 11829-11843.
24485460 Goddard LM, et al. 2014. Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation. Cell, 549-562.
24206663 Rong X, et al. 2013. LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition. Cell Metabolism, 685-697.
23525087 Do-Umehara HC, et al. 2013. Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ. Nature Immunology, 461-469.
Inflammatory Bowel Disease
PMID Publication
25105363 D'Alessio S, et al. 2014. VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease. Journal of Clinical Investigation, 3863-3878.
PMID Publication
24574341 Guinea-Viniegra J, et al. 2014. Targeting miR-21 to treat psoriasis. Science Translational Medicine, 225re1.
PMID Publication
37061529 L Kiss, et al. 2023. Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates. Nature Communications, 2160.
35486676 S Foss, et al. 2022. Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge. Science Immunology, eabj1640.
33633400 J Zeng, et al. 2021. Target-induced clustering activates Trim-Away of pathogens and proteins. Nature Structure and Molecular Biology, 278-289.
31613747 J Zeng, et al. 2019. Rare missense variants in the human cytosolic antibody receptor preserve antiviral function. Elife, e48339.
31582740 L Kiss, et al. 2019. A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases. Nature Communications, 4502.
30926239 M Bottermann, et al. 2019. Complement C4 Prevents Viral Infection through Capsid Inactivation. Cell Host Microbe, 617-629.
30796180 PML Ng, et al. 2019. Enhancing Antigen Cross-Presentation in Human Monocyte-Derived Dendritic Cells by Recruiting the Intracellular Fc Receptor TRIM21. Journal of Immunology, 2307-2319.
29667579 Claire Dickson† , et al. 2018. Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21. Elife, e32660.
26506431 Watkinson RE, et al. 2015. TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus. PLoS Pathology, e1005253.
26150489 Fletcher AJ, et al. 2015. Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21. PNAS: USA, 10014-10019.
25169018 Bidgood SR, et al. 2014. Translocalized IgA mediates neutralization and stimulates innate immunity inside infected cells. PNAS: USA, 13463-8.

Lipid Metabolism

PMID Publication
36522129 L Bideyan, et al. 2022. Hepatic GATA4 regulates cholesterol and triglyceride homeostasis in collaboration with LXRs. Genes Development, 1129-1144.
32111832 A Loregger, et al. 2020. Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism. Nature Communications, 1128.
29068315 Zhang L, et al. 2017. Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP. Elife, e28766.
28063500 Yun B, et al. 2017. Cellular Assays for Evaluating Calcium-Dependent Translocation of cPLA2α to Membrane. Methods in Enzymology, 71-99.
27665711 Mobin MB, et al. 2016. The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation. Nature Communications, 12848.
25440060 Walter KM, et al. 2014. Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy. Cell Metabolism, 882-897.
23416070 von Meyenn F, et al. 2013. Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism. Cell Metabolism, 436-447.
16459311 Wolfrum C, et al. 2006. Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion. Cell Metabolism, 99-110.
15793583 Wolfrum C, et al. 2005. Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis. Nature Medicine, 418-422.
15616563 Wolfrum C, et al. 2004. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature, 1027-1032.
12865419 C Wolfrum, et al. 2003. Role of Foxa-2 in adipocyte metabolism and differentiation. Journal of Clinical Investigation, 345-356.
PMID Publication
30355480 Gulyaeva, O., et al. 2018. Sox9-Meis1 inactivation is required for adipogenesis, advancing Pref-1+ to PDGFRα+ cells. Cell Reports, 1002-1017.
28192372 Wang J, et al. 2017. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. Journal of Clinical Investigation, 987-1004.
23152581 Halperin DS, et al. 2013. Vestigial-like 3 is an inhibitor of adipocyte differentiation. Journal of Lipid Research, 473-481.
22579288 Whittle AJ, et al. 2012. BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell, 871-885.
PMID Publication
23473036 Villanueva CJ, et al. 2013. Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs. Cell Metabolism, 423-435.


Hepatic Metabolism
PMID Publication
31692367 M Conde-Sieira, et al. 2020. Hypothalamic AMPKα2 regulates liver energy metabolism in rainbow trout through vagal innervation. American Journal of Physiology. Regulatory, integrative, and comparative physiology, R122-R134.
30460617 M Conde-Sieira, et al. 2019. Differential Role of Hypothalamic AMPKα Isoforms in Fish: an Evolutive Perspective. Molecular Neurobiology, 5051-5066.
28877455 Simcox J, et al. 2017. Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis. Cell Metabolism, 509-522.
Liver Disease
PMID Publication
37230004 V Ferreira, et al. 2023. Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition. Redox Biology, 102741.
35476518 C Priest, et al. 2022. Brap regulates liver morphology and hepatocyte turnover via modulation of the Hippo pathway. PNAS: USA, .
28480888 Porteiro B, et al. 2017. Hepatic p63 regulates steatosis via IKKβ/ER stress. Nature Communications, 15111.
21887698 Krützfeldt J, et al. 2012. MicroRNA-194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled-6. Hepatology, 98-107.
35294257 D Böck, et al. 2022. In vivo prime editing of a metabolic liver disease in mice. Science Translational Medicine, eabl9238.


Helicobacter Pylori
PMID Publication
32174134 EA Marcus, et al. 2020. Helicobacter pylori infection impairs chaperone-assisted maturation of Na-K-ATPase in gastric epithelium. American Journal of Physiology. Gastrointestinal and Liver Physiology, G931-G945.
Lymes Disease
PMID Publication
23141105 Ullmann AJ, et al. 2012. Immunization with adenoviral-vectored tick salivary gland proteins (SALPs) in a murine model of Lyme borreliosis. Ticks and Tick Borne Diseases, 160-163.
PMID Publication
23904160 Bladwin, SL, et al. 2013. Protection against tuberculosis with homologous or heterologous protein/vector vaccine approaches is not dependent on CD8+ T cells. Journal of Immunology, 2514-2525.


Muscle Disease
PMID Publication
31948476 C Whitmore, et al. 2020. The ERG1a potassium channel increases basal intracellular calcium concentration and calpain activity in skeletal muscle cells. Skeletal Muscle, 1.
23860742 Owens J, et al. 2013. Characterization of primary human skeletal muscle cells from multiple commercial sources. In Vitro Cellualer and Developmental Biology. Animal, 695-705.
Muscular Dystrophy
PMID Publication
32975514 AS Walimbe, et al. 2020. POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan. Elife, e61388.
27879205 Zhu Q, et al. 2016. Structure of protein O-mannose kinase reveals a unique active site architecture. Elife, e22238.
24682306 Saccone V, et al. 2014. HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles. Genes Development, 841-857.


PMID Publication
38569938 Deep, S.N., et al. 2024. Homocysteine-induced sustained GluN2A NMDA receptor stimulation leads to mitochondrial ROS generation and neurotoxicity. Journal of Biological Chemistry, 107253.
36823656 D Song, et al. 2023. Low-intensity pulsed ultrasound triggers a beneficial neuromodulation in dementia mice with chronic cerebral hypoperfusion via activation of hippocampal Fndc5/irisin signaling. Journal of Translational Medicine, 139.
33154371 RB Kasetti, et al. 2020. ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load. Nature Communications, 5594.
30294906 Karuppagounder, S.S., et al. 2018. N‐acetylcysteine targets 5 lipoxygenase‐derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following …. Annals of Neurology, 854-872.
30074985 Chan, J.P., et al. 2018. The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain. PLoS Biology, e2006443.
28402971 Kichev A, et al. 2017. Implicating Receptor Activator of NF-κB (RANK)/RANK Ligand Signalling in Microglial Responses to Toll-Like Receptor Stimuli. Developmental Neuroscience, 192-206.
26936506 Karuppagounder SS, et al. 2016. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Science Translational Medicine, 328ra29.
23103326 Brim BL, et al. 2013. Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor. Behavior Brain Research, 211-226.
Alzheimer’s Disease
PMID Publication
37453419 A Kumar, et al. 2023. 2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience. Neuron, 2831-2846.
30617325 MV Lourenco, et al. 2019. Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models. Nature Medicine, 165-175.
28049840 McEwan WA, et al. 2017. Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation. PNAS: USA, 574-579.
Neurodegenerative Disease
PMID Publication
37942487 Murray SJ, et al. 2023. Efficacy of dual intracerebroventricular and intravitreal CLN5 gene therapy in sheep prompts the first clinical trial to treat CLN5 Batten disease. Frontiers in Pharmacology, 1212235.
37614821 NL Mitchell, et al. 2023. Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease. Frontiers in Genetics, 1212228.
36272468 V Ferreira, et al. 2022. Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight. Metabolism, 155335.
35508140 Tuck BJ, et al. 2022. Cholesterol determines the cytosolic entry and seeded aggregation of tau. Cell Reports, 110776.
Batten’s Disease
PMID Publication
37246363 NL Mitchell, et al. 2023. Characterization of neuropathology in ovine CLN5 and CLN6 neuronal ceroid lipofuscinoses (Batten disease). Developmental Neurobiology, 127-142.
Parkinsons Disease
PMID Publication
24117733 Luerman GC, et al. 2014. Phosphoproteomic evaluation of pharmacological inhibition of leucine-rich repeat kinase 2 reveals significant off-target effects of LRRK-2-IN-1. Journal of Neurochemistry, 561-576.
PMID Publication
31056284 I Alim, et al. 2019. Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Cell, 1262-1279.
Spinal Cord Injury
PMID Publication
25740503 North HA, et al. 2015. β1-Integrin alters ependymal stem cell BMP receptor localization and attenuates astrogliosis after spinal cord injury. Journal of Neuroscience, 3725-3733.


PMID Publication
34675439 E Milbank, et al. 2021. Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation. Nature Metabolism, 1415-1431.
33080217 V Heras, et al. 2020. Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty. Cell Metabolism, 951-966.
31775033 D Yi, et al. 2019. Zc3h10 Acts as a Transcription Factor and Is Phosphorylated to Activate the Thermogenic Program. Cell Reports, 2621-2633.
30448371 R Rodríguez-Rodríguez, et al. 2019. CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity. Molecular Metabolism, 75-85.
30104247 Seoane-Collazo, P., et al. 2018. SF1-Specific AMPKα1 deletion protects against diet-induced obesity. Diabetes, 2213-2226.
30018241 Liñares-Pose, L., et al. 2018. Genetic targeting of GRP78 in the VMH improves obesity independently of food intake. Genes, 357.
29562231 Devram S. Ghorpade, et al. 2018. Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance. Nature, 673-677.
29478099 Stadion, M., et al. 2018. Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans. Diabetologia, 1167-1179.
28846071 Rong X, et al. 2017. ER phospholipid composition modulates lipogenesis during feeding and in obesity. Journal of Clinical Investigation, 3640-3651.
27634226 Contreras C, et al. 2017. Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity. Diabetes, 87-99.
26150485 Zeng W, et al. 2015. Reanalysis of parabiosis of obesity mutants in the age of leptin. PNAS: USA, E3874-E3882.
25284795 Contreras C, et al. 2014. Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance. Cell Reports, 366-377.
24917578 Beiroa D, et al. 2014. GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK. Diabetes, 3346-3358.
22692684 Vogel H, et al. 2012. Loss of function of Ifi202b by a microdeletion on chromosome 1 of C57BL/6J mice suppresses 11β-hydroxysteroid dehydrogenase type 1 expression and development of obesity. Human Molecular Genetics, 3845-3857.
22682225 Haas JT, et al. 2012. Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. Cell Metabolism, 873-884.
22315316 Martínez de Morentin PB, et al. 2012. Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes, 807-817.
PMID Publication
33449689 BT Milliken, et al. 2021. Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis. Journal of Medicinal Chemistry, 1127-1138.
27110486 Okada, K., et al. 2016. Thioesterase superfamily member 1 suppresses cold thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids in brown adipose tissue. Molecular Metabolism, 340-351.
26909312 Quiñones M, et al. 2015. Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance. Molecular Metabolism, 961-970.
Insulin Resistance
PMID Publication
31952989 HP Nguyen, et al. 2020. Aifm2, a NADH Oxidase, Supports Robust Glycolysis and Is Required for Cold- and Diet-Induced Thermogenesis. Molecular Cel, 600-617.


PMID Publication
27650499 Xiao X, et al. 2016. A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis. Journal of Biological Chemistry, 23224-23236.
23955596 Witt H, et al. 2013. Variants in CPA1 are strongly associated with early onset chronic pancreatitis. Nature Genetics, 1216-1220.
22942235 Beer S, et al. 2012. Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk. Gut, 1616-1624.
PMID Publication
25862608 Szabó A, et al. 2015. A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding. Biochmica et Biophysica Acta, 1372-1379.


PMID Publication
38605139 Schofield, L.G., et al. 2024. The soluble (pro)renin receptor promotes a preeclampsia-like phenotype both in vitro and in vivo. Hypertension Research, .
38099297 Al-Mutairy EA, et al. 2023. Wild-type S100A3 and S100A13 restore calcium homeostasis and mitigate mitochondrial dysregulation in pulmonary fibrosis patient-derived cells. Frontier in Cells and Developmental Biology, 1282868.
36859533 B Jiménez-Gómez, et al. 2023. Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice. Nature Communications, 1172.
35833903 HC Do-Umehara, et al. 2022. Suppression of Allergic Asthma by Loss of Function of Miz1-mediated Th1 Skewing. American Journal of Respiratory Cell and Molecular Biology, 346-359.
35714602 Wang C, et al. 2022. Triangulating variation in the population to define mechanisms for precision management of genetic disease. Structure, 1190-1207.
30753450 F Anglès, et al. 2019. HDAC inhibitors rescue multiple disease-causing CFTR variants. Human Molecular Genetics, 1982-2000.
29924966 Hutt, D.M., et al. 2018. A proteomic variant approach (ProVarA) for personalized medicine of inherited and somatic disease. Journal of Molecular Biology, 2951-2973.
28874464 Cerniello FM, et al. 2017. MAS1 Receptor Trafficking Involves ERK1/2 Activation Through a β-Arrestin2-Dependent Pathway. Hypertension, 982-989.
27913421 Yanagisawa H, et al. 2017. Role of IL-17A in murine models of COPD airway disease. American Journal of Physiology. Lung Cellular and Molecular Physiology, L122-L130.
26109638 Hashimoto M, et al. 2015. TGF-β-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease. Journal of Immunology, 1182-1190.
23371060 Allen-Gipson DS, et al. 2013. Smoke extract impairs adenosine wound healing: implications of smoke-generated reactive oxygen species. American Journal of Respiratory Cell and Molecular Biology, 665-673.
Lung Development
PMID Publication
23499839 Berkelhamer SK, et al. 2013. Developmental differences in hyperoxia-induced oxidative stress and cellular responses in the murine lung. Free Radical Biology and Medicine, 51-60.
Lung Disease
PMID Publication
35998281 Ahangari F, et al. 2022. Saracatinib, a selective Src kinase inhibitor, blocks fibrotic responses in preclinical models of pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine , 1463-1479.
35931677 Y Chen, et al. 2022. Club cells employ regeneration mechanisms during lung tumorigenesis. Nature Communications, 4557.
27452368 Schlingmann B, et al. 2016. Regulation of claudin/zonula occludens-1 complexes by hetero-claudin interactions. Nature Communications, 12276.
26999599 Fink L, et al. 2016. Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection. The Journal of Clinical Investigation, 1566-1580.
Lung Inflammation
PMID Publication
34899681 J Yang, et al. 2021. miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury. Frontiers in Immunology, 700933.
28620381 Brazee PL, et al. 2017. FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury. Frontiers in Immunology, 623.
Pulmonary Disease
PMID Publication
23136161 Jakob P, et al. 2012. Loss of angiomiR-126 and 130a in angiogenic early outgrowth cells from patients with chronic heart failure: role for impaired in vivo neovascularization and cardiac repair capacity. Circulation, 2962-2975.
22634619 Luzina IG, et al. 2012. Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion. Journal of Immunology, 403-410.


PMID Publication
32240312 YJ Jung, et al. 2020. SIRT2 is involved in cisplatin-induced acute kidney injury through regulation of mitogen-activated protein kinase phosphatase-1. Nephrology, Dialysis, Transplantation, 1145-1156.
30385718 Jaykumar, A.B., et al. 2018. Role of Alström syndrome 1 in the regulation of blood pressure and renal function. JCI Insight, e95076.
27551042 Caceres PS, et al. 2016. Vesicle-associated Membrane Protein 3 (VAMP3) Mediates Constitutive Trafficking of the Renal Co-transporter NKCC2 in Thick Ascending Limbs: ROLE IN RENAL FUNCTION AND BLOOD PRESSURE. Journal of Biological Chemistry, 22063-22073.
22977238 Ares GR, et al. 2012. Dynamin2, clathrin, and lipid rafts mediate endocytosis of the apical Na/K/2Cl cotransporter NKCC2 in thick ascending limbs. Journal of Biological Chemistry, 37824-37834.
22896039 Hong NJ, et al. 2012. NADPH oxidase 4 mediates flow-induced superoxide production in thick ascending limbs. American Journal of Physiology. Renal Physiology, F1151-F1156.
22875785 Massey KJ, et al. 2012. Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4. American Journal of Physiology. Cell Physiology, C781-789.
Renal Injury
PMID Publication
26911537 Jung M, et al. 2016. Macrophage-derived Lipocalin-2 contributes to ischemic resistance mechanisms by protecting from renal injury. Scientific Reports, 21950.

Reproductive System

PMID Publication
25340710 Swiderski RE, et al. 2014. A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling. PLoS Genetics, e1004689.
PMID Publication
30348767 Roa, J., et al. 2018. Metabolic regulation of female puberty via hypothalamic AMPK–kisspeptin signaling. PNAS: USA, E10758-E10767.
30304681 González-García, I., et al. 2018. Estradiol regulates energy balance by ameliorating hypothalamic ceramide-induced ER stress. Cell Reports, 413-423.
28683288 Martínez-Sánchez N, et al. 2017. Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance. Cell Matabolism, 212-229.
28218624 Ahmed K, et al. 2017. Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility. Journal of Clinical Investigation, 1061-1074.
27913573 Martínez-Sánchez N, et al. 2017. Thyroid hormones induce browning of white fat. Journal of Endocrinology, 351-362.
24856932 Martínez de Morentin PB, et al. 2014. Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK. Cell Metabolism, 41-53.


PMID Publication
37296170 H Vatandaslar, et al. 2023. In vivo PAR-CLIP (viP-CLIP) of liver TIAL1 unveils targets regulating cholesterol synthesis and secretion. Nature Communications, 3386.
36646933 N Mathis, et al. 2023. Predicting prime editing efficiency and product purity by deep learning. Nature Biotechnology, 1151-1159.
32497496 X Li, et al. 2020. High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down. Molecular Cell, 167-179.
32497496 X Li, et al. 2020. High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down. Molecular Cell, 167-179.
32143184 J Latorre, et al. 2020. Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes. EBioMedicine, 102697.
24355758 Sehgal A, et al. 2014. Tissue-specific gene silencing monitored in circulating RNA. RNA, 143-149.
16258535 Krutzfeldt J, et al. 2005. Silencing of microRNAs in vivo with 'antagomirs'. Nature, 685-689.


PMID Publication
37830821 JA Misplon, et al. 2023. Adenoviral-vectored universal influenza vaccines administered intranasally reduce lung inflammatory responses upon viral challenge 15 months post-vaccination. Journal of Virology, e0067423.
36377872 OE Harwood, et al. 2022. Transient T Cell Expansion, Activation, and Proliferation in Therapeutically Vaccinated Simian Immunodeficiency Virus-Positive Macaques Treated with N-803. Journal of Virology, e0142422.
36190241 AL Ellis-Connell, et al. 2022. Control of Simian Immunodeficiency Virus Infection in Prophylactically Vaccinated, Antiretroviral Treatment-Naive Macaques Is Required for the Most Efficacious CD8 T Cell Response during Treatment with the Interleukin-15 Superagonist N-803. Journal of Virology, e0118522.
35023731 LF Barnes, et al. 2022. Analysis of Recombinant Adenovirus Vectors by Ion Trap Charge Detection Mass Spectrometry: Accurate Molecular Weight Measurements beyond 150 MDa. Analytical Chemistry, 1543-1551.
33796119 N Pedreño-Lopez, et al. 2021. Non-neutralizing Antibodies May Contribute to Suppression of SIVmac239 Viremia in Indian Rhesus Macaques. Frontiers in Immunology, 657424.
33627390 S Dhakal, et al. 2021. Effect of an Adenovirus-Vectored Universal Influenza Virus Vaccine on Pulmonary Pathophysiology in a Mouse Model. Journal of Virology, e02359-20.
33441339 K Sangare, et al. 2021. The immunological impact of adenovirus early genes on vaccine-induced responses in mice and nonhuman primates. Journal of Virology, e02253-20.
31315990 SA Abdulhaqq, et al. 2019. Vaccine-Mediated Inhibition of the Transporter Associated with Antigen Processing Is Insufficient To Induce Major Histocompatibility Complex E-Restricted CD8+ T Cells in Nonhuman Primates. Journal of Virology, e00592-19.
30037481 Price, G.E., et al. 2018. Reduction of influenza virus transmission from mice immunized against conserved viral antigens is influenced by route of immunization and choice of vaccine antigen. Vaccine, 4910-4918.
29875239 , et al. 2018. Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication. Journal of Virology, e00690-18.
27055234 García M, et al. 2016. Age Dependence of Immunity Induced by a Candidate Universal Influenza Vaccine in Mice. PLoS One, .
26374823 Gabitzsch ES, et al. 2015. The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic. Oncotarget, 31344-31359.
26355094 Malczyk AH, et al. 2015. A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform. Journal of Virology, 11654-11667.
26292326 Martins MA, et al. 2015. Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection. Journal of Virology, 10802-10820.
26018172 Volz A, et al. 2015. Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein. Journal of Virology, 8651-8656.
24741098 Martins MA, et al. 2014. Vaccination with Gag, Vif, and Nef gene fragments affords partial control of viral replication after mucosal challenge with SIVmac239. Journal of Virology, 7493-7516.
24509082 Subramanian M, et al. 2014. An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. Journal of Clinical Investigation, 1296-1308.
24328381 Barlow PG, et al. 2014. Antiviral potential of cathelicidins. Future Microbiology, 55-73.
23777453 Rivers K, et al. 2013. Comparison of the effectiveness of antibody and cell-mediated immunity against inhaled and instilled influenza virus challenge. Virology Journal, 198.
23596321 Eyles JE, et al. 2013. Nonreplicating vaccines can protect african green monkeys from the memphis 37 strain of respiratory syncytial virus. The Journal of Infectious Diseases, 319-329.
23103198 Bright H, et al. 2012. The efficacy of HSV-2 vaccines based on gD and gB is enhanced by the addition of ICP27. Vaccine, 7529-7535.
23041546 Gabitzsch ES, et al. 2012. Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform. Vaccine, 7265-7270.
23023123 Mudd PA, et al. 2012. Vaccine-induced CD8+ T cells control AIDS virus replication. Nature, 129-133.
22586427 Thomson CA, et al. 2012. Pandemic H1N1 Influenza Infection and Vaccination in Humans Induces Cross-Protective Antibodies that Target the Hemagglutinin Stem. Frontiers in Immunology, 87.
PMID Publication
30541854 MA Martins, et al. 2019. The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques. Journal of Virology, e01626-18.
PMID Publication
34162739 A Tscherne, et al. 2021. Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination. PNAS: USA, .
PMID Publication
27317453 Kaveh DA, et al. 2016. Parenteral adenoviral boost enhances BCG induced protection, but not long term survival in a murine model of bovine TB. Vaccine, 4003-4011.


PMID Publication
26337747 Rice AE, et al. 2015. An HPV-E6/E7 immunotherapy plus PD-1 checkpoint inhibition results in tumor regression and reduction in PD-L1 expression. Cancer Gene Therapy, 454-462.
PMID Publication
35449595 TW Powers, et al. 2022. Identification of Recombinant Chimpanzee Adenovirus C68 Degradation Products Detected by AEX-HPLC. Frontiers in Bioengineering and Biotechnology, 753481.
Herpes Simplex Virus
PMID Publication
36692302 JH Arbuckle, et al. 2023. Deletion of the Transcriptional Coactivator HCF-1 In Vivo Impairs the Removal of Repressive Heterochromatin from Latent HSV Genomes and Suppresses the Initiation of Viral Reactivation. mBio, e0354222.
30541854 MA Martins, et al. 2019. The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques. Journal of Virology, e01626-18.
30541854 MA Martins, et al. 2019. The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques. Journal of Virology, e01626-18.
26292326 Martins MA, et al. 2015. Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection. Journal of Virology, 10802-10820.
24741098 Martins MA, et al. 2014. Vaccination with Gag, Vif, and Nef gene fragments affords partial control of viral replication after mucosal challenge with SIVmac239. Journal of Virology, 7493-7516.
24578133 Xie X, et al. 2014. The basic domain of HIV-tat transactivating protein is essential for its targeting to lipid rafts and regulating fibroblast growth factor-2 signaling in podocytes isolated from children with HIV-1-associated nephropathy. Journal of American Society of Nephrology, 1800-1813.
23023123 Mudd PA, et al. 2012. Vaccine-induced CD8+ T cells control AIDS virus replication. Nature, 129-133.
immune Response
PMID Publication
32943673 G Hotter, et al. 2020. The influenza virus NS1A binding protein gene modulates macrophages response to cytokines and phagocytic potential in inflammation. Scientific Reports, 15302.
PMID Publication
25190799 Tam JC, et al. 2014. Intracellular sensing of complement C3 activates cell autonomous immunity. Science, 1256070.
PMID Publication
34452363 S Halwe, et al. 2021. Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection. Viruses, 1498.
32616594 L Sauerhering, et al. 2020. Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-λ in vitro and in mice. The European Respiratory Journal, 1901826.

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