Anti-Cav2.3 Recombinant Chicken Chimeric mAb

Name: Anti-Cav2.3 Recombinant Chicken Chimeric mAb
Brand: Aves Labs
SKU: 78-531
Price: 481.0 USD
Availability: InStock

Our chicken Anti-Cav2.3 recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N493/22. It detects human, mouse, and rat Cav2.3 and is purified by affinity chromatography. Works in ELISA, ICC, IHC, WB.

Immunohistochemistry staining of adult rat brain section using anti-Cav2.3 NeuroMab mouse monoclonal antibody (Clone N493/22). The variable region of this antibody was used to generate recombinant chicken chimeric anti-Cav2.3 antibody (78-531).

Western blotting of rat brain membrane with anti-Cav2.3 recombinant chicken mAb antibody (Cat No. 78-531) recognizing endogenous Cav2.3 at ~250 kDa. The chicken mAb was detected with anti-chicken-HRP (Cat No. 80-1000-HRP).

Immunohistochemistry staining of adult rat brain section using anti-Cav2.3 NeuroMab mouse monoclonal antibody (Clone N493/22). The variable region of this antibody was used to generate recombinant chicken chimeric anti-Cav2.3 antibody (78-531).

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Chicken

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

Trial Size

SKU: 78-531

Volume: 100 µL

Variant

Price:

$481.00

Quantity:

Ships: 1-2 business days

Product Details

Isotype

IgY

Applications

ELISA, ICC, IHC, WB

Host Species

Chicken

Species Reactivity

Human, Mouse, Rat

Synonyms

BII; voltage-dependent R-type calcium channel subunit alpha-1E; CACNL1A6; Cav2.3; gm139; brain calcium channel II; calcium channel; R type; alpha-1 polypeptide; voltage-dependent calcium channel alpha 1E subunit; voltage-gated calcium channel alpha subunit Cav2.3; Cacna1e

UniProt ID

Q61290
UniProt Summary: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells. They are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.

NCBI Gene ID

777

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Anti-Cav2.3 Recombinant Chicken Chimeric mAb

SKU: 78-531

Product Details

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