Black-Gold II, a myelin stain, is a novel haloaurophosphate complex that has a particular affinity for myelin and can therefore be used to localize myelin within the central nervous system and characterize specific myelin changes associated with exposure to diverse neurotoxicants, including kainic acid, domoic acid, 3-nitropionic acid, Fluoro-Gold and isoniazid.
This novel tracer can be used to localize both normal and pathological myelin. Black Gold II can also be combined with other histochemical markers, including Nissl stains, retrogradely transported fluorescent tracers, and fluorescent markers for neuronal degeneration.
The advantages of our Black-Gold II include high resolution, high contrast, short histochemical processing time, versatility and consistent reproducibility.
