Lectins are proteins that specifically bind to carbohydrate moieties, targeting sugar groups on glycoproteins and glycolipids. For example, WGA binds to N-acetyl glucosamine and sialic acid residues, ConA targets α-mannosyl and α-glucosyl residues, PNA shows preference for Galβ1, and UEA binds to α-linked fucose residues. Their binding can be inhibited by adding a high concentration of the corresponding sugar. Unconjugated lectins can be coupled to beads for glycoprotein purification, while conjugated lectins are used for detecting glycoproteins in histochemical and immunoflourescence studies.
Our WGA, ConA, PNA, and UEA lectins are available conjugated with FITC - a fluorescent dye to allow visualization under fluorescence microscopy or detection in flow cytometry, or labeled with biotin - a small molecule that binds strongly to avidin or streptavidin.
Please see below for our full catalog:
