Antibodies for Neuroscience Research

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Staining of a tissue section through the midbrain region of an adult mouse for GFP (green) and Tryptophan Hydroxylase-positive neurons (red).Pyramidal neurons in the hippocampal formation of a neonatal mouse brain. Tissue was paraformaldehyde-fixed (4%) and paraffin-embedded. GFP staining is in green in left panel.
Aves Labs Anti-Green Fluorescent Protein (GFP) Antibody
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Immunofluorescence staining of cultured rat hippocampal neurons with K28/43 (green) and K57/1 (red, Kv4.2).Immunoblot against adult rat brain membranes (RBM) and adult mouse hippocampal membranes (MHM) from PSD-95 and -93 knockout (KO) mice probed with K28/43 (left) or K28/86 (right) TC supe. Mouse samples courtesy of Richard Huganir (Johns Hopkins University, Howard Hughes Medical Institute).
NeuroMab Anti-PSD-95 Antibody
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Glial Fibrillary Acidic Protein (GFAP) immunostaining (red) of mixed cortical mouse brain cultures (1:500 dilution). Secondary antibody is Texas Red goat anti-chicken IgY. The blue is DAPI staining of nuclei of all cells, including non-GFAP-positive cells. Photo courtesy of Dr. Gerry Shaw, Univ. Florida.Representative section of formalin fixed, paraffin-embedded rat brain showing staining of GFAP. The sections were stained with Aves Labs anti-GFAP antibody (visualized in green)  (Cat. GFAP) at 1:500 dilution. The stained sections were mounted with Antibodies Incorporated FluoroshieldTM with DAPI and DABCO mounting medium (Cat. AR-6505). DAPI nuclear stain (blue) shows cell nuclei. Anti-GFAP specifically stains the astrocytes in the rat brain.
Aves Labs Anti-Glial Fibrillary Acidic Protein (GFAP) Antibody
$301
Immunofluorescence staining of axon initial segments in adult rat cortex with N106/36 (red) and bIV- spectrin rabbit polyclonal (green). Image courtesy of Matt Rasband (Baylor College of Medicine).Immunofluorescence staining of nodes of Ranvier in adult rat optic nerve with N106/36 (red) and Caspr rabbit polyclonal (green). Image courtesy of Matt Rasband (Baylor College of Medicine).
NeuroMab Anti-Ankyrin-G (Staining) Antibody
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Immunostaining of paraformaldehyde-fixed (4%) free-floating sections (50 µm) of the posterior area of the brain (ventral tegmental area/substania nigra) of an adult mouse brain containing TH+ neurons. TH antibody (Cat. TYH-0020) dilution @ 1:1500 with secondary detection of the chicken antibody with Alexa-647 anti-chicken IgY, 1:1000. (Image courtesy of Antonella Rios, Duke University.)Immunostaining of paraformaldehyde-fixed (4%) free-floating sections (50 µm) of the posterior area of the brain (ventral tegmental area/substania nigra) of an adult mouse brain containing TH+ neurons. TH antibody (Cat. TYH-0020) dilution @ 1:1500 with secondary detection of the chicken antibody with Alexa-647 anti-chicken IgY, 1:1000. (Image courtesy of Antonella Rios, Duke University.)
Aves Labs Anti-Tyrosine Hydroxylase (TYH) Antibody
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Immunofluorescence of the ventricular zone of E14 mouse brain (frozen section) labeled with Anti-Arl13b (red, Cat No. 75-287, 1:1000) and CEP152 (Green). The blue is DAPI staining of nuclear DNA. Image kindly provided by Koh-ichi Nagata, Nagoya University Graduate School of Medicine.Immunoblot versus crude membranes from adult rat brain (RBM) and pellet/lysate fractions of wild-type (WT) and Arl13b knockout (KO) mouse embryonic fibroblasts (MEF) probed with N295B/66 TC supe (left), rabbit polyclonal (middle) and N52A/42 TC supe (right). MEF cells courtesy of Laura Mariani and Tamara Caspary (Emory University SOM).
NeuroMab Anti-Arl13b Antibody
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Immunostaining of retinal ganglion cells from the blind mole rat, Spalax Ehrenbergi, stained for RBPMS (red), melanopsin (green), and DAPI (blue). Credit: Jens Hannibal, Ass. Professor, MD, PhD., DmSc. Dept. Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark.Western blot of rat heart lysate showing specific labeling of the ~24 kDa RBPMS protein.
PhosphoSolutions Anti-RBPMS Antibody
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Cortical neuron from a neo-natal mouse brain culture immunocytochemically stained for NF-H immunoreactivity (1:5000 dilution). Secondary antibody (fluorescein-labeled goat anti-chicken IgY, (1:1000 dilution)Confocal micrographs of DRG cryosections from WT mouse double-labeled with antibodies against caldendrin (green) and NF200 (Cat. NFH, 1:1000, purple) or peripherin (Cat. PER, 1:1000, purple). Arrows and arrowheads indicate cells in which caldendrin is or is not, respectively, co-localized with NF200 or peripherin. Results are representative of at least 3 independent experiments. Scale bar, 100 µm. Image from publication CC-BY-4.0. PMID:36788334
Aves Labs Anti-NFH (Neurofilament Heavy Chain) Antibody
$301
iPSC-DA neuronal cultures from control and LRRK2R1441C patient lines were treated with DMSO or CCCP (24 h, 10 μM) then fixed, stained for LRRK2 (Cat. 75-253, 1:100), TOM20 and MIRO1. Image from publication CC-BY-4.0. PMID:37384414Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).
NeuroMab Anti-LRRK2/Dardarin, C-Terminus Antibody
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Immunostaining of paraformaldehyde-fixed (4%) neonatal mouse brain cultures showing β-Tubulin 3 immunostaining (green, 1:1000). Red staining is rabbit-anti-GFAP, blue is DAPI nuclear counterstain. Secondary antibodies were fluorescein-labeled goat anti-chicken IgY; Texas Red-labeled goat anti-rabbit IgG. Image from Dr. Gerry Shaw (EnCor Biotechnology).Immunostaining of paraformaldehyde-fixed (4%) cultures of SpH64 neuroblastoma cells showing β-Tubulin 3 immunostaining (green, 1:1000). Red staining is rabbit-anti-actin (1:1000); blue is DAPI nuclear counterstain. Secondary antibodies were fluorescein-labeled goat anti-chicken IgY (Cat. F-1005, 1:1000); Texas Red-labeled goat anti-rabbit IgG. Page Balisch (University of Arizona).
Aves Labs Anti-Beta-Tubulin 3 (TUJ) Antibody
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Immunofluoresence of COS7 cells expressing mCherry using chicken anti-mCherry antibody (green) and showing mCherry autofluorescence (red). Blue is DAPI nuclear stain showing nuclei of both transfected and untransfected cells. Staining shows 100% correspondence between chicken anti-mCherry signal and mCherry autofluoresence in transfected cells.IMCD3 cells transfected with Arl13b-mCherry​ and stained with Anti-mCherry Antibody (Cat. MCHERRY, 1:300) and visualized​ with A594 anti-chicken secondary antibody. ​ As expected, cytoplasmic and ciliary signals are observed in transfected cells.​ Image kindly provided by Svetlana Makova, Yale University.
Aves Labs Anti-mCherry Antibody
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Immunoblot against lysates from wild-type (+/+) and RGS14 knockout (-/-) mouse brains probed with N133/21. Data courtesy of John Hepler (Emory).Coronal section from a C57BL/6J mouse showing the hippocampus co-stainedwith RGS14 (Cat. 75-170, 1:500; pink) and CaMKII alpha (green). The merged image is shown on the right. Image from publication CC-BY-4.0. PMID:36971428
NeuroMab Anti-RGS14 Antibody
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Immunolabeling of principal neurons in the mouse neocortex specifically labeling Kv2.1 channels (1:500). The image is from a CLSM stack, pixel size is 100 nm. The image is kindly provided by Csaba Cserep, Institute of Experimental Medicine, Budapest, Hungary.Immunoblot on adult mouse brain membranes from two wild-type mice (MBM-WT) and one Kv2.1 knockout (MBM-Kv2.1-KO) mouse. Samples courtesy of Dr. Jeanne Nerbonne, Washington University School of Medicine.
NeuroMab Anti-Kv2.1 K+ Channel Antibody
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Adult rat hippocampus immunohistochemistry.Immunolabeling of Nav1.1 (Cat. 75-023, 1:250) showing an increased expression in the Dorsal Root Ganglia of NaV1.7 knockout mice when compared to control mice. Image from publication. PMID: 39559752.
NeuroMab Anti-Nav1.1 Na+ Channel Antibody
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Immunostaining of mouse retinal ganglion cells showing specific immunolabeling of RBPMS (1:1000) in red. Photo courtesy of Allen Rodriguez, University of California, Los Angeles.Immunostaining of cat retina showing specific immunolabeling of RBPMS. Photo courtesy of Emily Brinker, Auburn University.
PhosphoSolutions Anti-RBPMS Antibody
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Representative section of formalin fixed, paraffin-embedded rat brain hippocampus region showing staining of GFAP. The sections were stained with Antibodies Incorporated anti-GFAP antibody (visualized in green)  (Cat. 75-240) at 1:500 dilution. The stained sections were mounted with Antibodies Incorporated FluoroshieldTM with DAPI and DABCO mounting medium (Cat. AR-6505). DAPI nuclear stain (blue) shows cell nuclei. Anti-GFAP specifically stains the astrocytes in the rat brain.Adult WT (left) and KO (right) mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit anti- Kv2.1 (red). Brain samples courtesy of Albee Messing, University of Wisconsin at Madison.
NeuroMab Anti-GFAP Antibody
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Immunofluorescence of AIF1/IBA1-FLAG transfected COS-7 cells using chicken α-AIF1/IBA1 (green) and mouse α-flag tag (red). Yellow/orange staining shows 100% correspondence between the two antibodies for recognition of transfected cells. Blue staining is DAPI and stains nuclei of both transfected and untransfected cells.Western blot of rat brain membrane lysate using chicken α-AIF1/IBA1 showing specific immunolabeling of endogenous AIF1/IBA1 at ~17kDa.
Aves Labs Anti-IBA1/AIF1 Antibody
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Immunoblot on crude membrane fractions from whole mouse (MBM) and rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with A12/18 (left) and N52A/42 (right) TC supe.Adult rat brain immunohistochemistry.
NeuroMab Anti-Pan-Neurofascin (Extracellular) Antibody
$394
Immunofluorescence staining of 14 DIV cultured rat cortical neuron with N355/1. Image courtesy of Brad Elmer and Kim McAllister (UCD).Adult rat hippocampus immunohistochemistry.
NeuroMab Anti-GluA1/GluR1 Glutamate Receptor Antibody
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Adult rat brain membrane immunoblot.Adult rat hippocampus immunohistochemistry.
NeuroMab Anti-CASPR/Neurexin IV Antibody
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MAP-2 immunoreactivity in neurosphere cultures from an e18 mouse brain (1:1000 dilution, green); 2˚ antibody was a fluorescein-labeled goat anti-chicken IgY (Aves Labs Cat No. F-1005, 1:500 dilution). Blue staining is DAPI nuclear stain. (Hoda Ilias, Aves Labs.)Neonatal mouse brain cortical cultures were stained with Aves Labs MAP2 (green) and GFAP (red, rabbit antibody); Blue is DAPI nuclear stain. Photo courtesy of Dr. Gerry Shaw, Univ. Florida.
Aves Labs Anti-Microtubule-Associated Protein (MAP2) Antibody
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Transfected cell immunofluorescence: COS cells expressing GFP. Blue = Hoechst nuclear stain, Green = GFP, Red = N86/8.Transfected cell immunoblot extracts of COS cells transfected with GFP; GFP-tagged HCN2, FGF11/FHF3 FGF13/FHF2 and BKBeta2; or untagged Kv2.1 plasmid and probed with N86/8 TC supe.
NeuroMab Anti-GFP Antibody
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Immunohistochemical staining of MBP (RED) in the hippocampal region of a transgenic adult mouse brain. This particular transgenic mouse expresses low levels of GFP autofluorescence under control of an actin promoter region. The anti-MBP antibody (Aves Labs) was used at a 1:1000 dilution. Dr. Felix Eckenstein, University of Vermont.Immunoblot images of MAG and MBP (Cat. MBP, 1:2000) in the somatosensory cortex of wildtype and GluD1 KO. Significant increase in MAG (***p < 0.0001, unpaired t-test) and MBP (*p < 0.0104, unpaired t-test) was found in GluD1 KO mice compared to wildtype. Image from publication CC-BY-4.0. PMID:37983226
Aves Labs Anti-Myelin Basic Protein (MBP) Antibody
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Immunolabeling of postnatal 14 mouse CA3 (Axonal Initial Segment, Parvalbumin positive interneuron) labeling Kv1.2 (75-008, 1:200, yellow) Parvalbumin (magenta), and Ankyrin G (cyan). Mice were transcardially perfused with cold 4% PFA in PBS, then brain removed and postfixed overnight. 50 uM slices as floating sections, antigen retrieval performed with sodium citrate at 80 C for 30 min. before immunolabeling. Images from J. Ramirez-Franco and O. El Far, Aix-Marseille Université and INSERM.Immunolabeling of permeabilized HEK293 cells specifically labeling intracellular Kv1.2 (Cat. 75-008, 1:200, red) and DAPI labelling DNA (blue). Images kindly provided by Ivan Talucci and Maric Hans, Rudolf Virchow Center for Integrative and Translational Bioimaging.
NeuroMab Anti-Kv1.2 K+ Channel Antibody
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