Anti-TASK1 Potassium Channel Antibody FL490 Conjugate (N374/48)

Name: Anti-TASK1 Potassium Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-357-FL490
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

550

594

650

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N374/48

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Kcnk3 Task Task1

Molecular Weight

50 kDa

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Volume: 200 µL

Variant

Price:

$445

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Bulk Order Anti-TASK1 Potassium Channel Antibody FL490 Conjugate

Product Details

Target

TASK1 potassium channel

Target Description

Potassium two pore domain channel subfamily K member 3 is encoded by the gene KCNK3. KCNK3 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK3 is a pH dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from the potassium ion concentration on either side of the membrane, with it functioning as an outward rectifier when the external potassium concentration is low, and it functioning as an internal rectifier when the external potassium concentration is high. KCNK3 is expressed in the heart, lung, brain, liver, kidney, and skeletal muscle. Diseases associated with KCNK3 include Pulmonary Hypertension Primary 4 and Heritable Pulmonary Arterial Hypertension.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N374/48

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnk3 Task Task1

Molecular Weight

50 kDa

Antigen

Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1 (accession number O54192) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940196

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with TASK3

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1)

UniProt Details

UniProt (Human): O14649
UniProt (Immunogen Species): O54912

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Anti-TASK1 Potassium Channel Antibody FL490 Conjugate (N374/48)

Available Conjugates

Anti-TASK1 Potassium Channel Antibody FL490 Conjugate
SKU: 75-357-FL490

Bulk Order Anti-TASK1 Potassium Channel Antibody FL490 Conjugate

Product Details

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Anti-TASK1 Potassium Channel Antibody FL490 Conjugate (N374/48)

Available Conjugates

Anti-TASK1 Potassium Channel Antibody FL490 Conjugate SKU: 75-357-FL490

Bulk Order Anti-TASK1 Potassium Channel Antibody FL490 Conjugate

Product Details

Anti-TASK1 Potassium Channel Antibody FL490 Conjugate
SKU: 75-357-FL490