Bulk Order Anti-TASK1 Potassium Channel Antibody FL594 Conjugate
TASK1 potassium channel
Potassium two pore domain channel subfamily K member 3 is encoded by the gene KCNK3. KCNK3 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK3 is a pH dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from the potassium ion concentration on either side of the membrane, with it functioning as an outward rectifier when the external potassium concentration is low, and it functioning as an internal rectifier when the external potassium concentration is high. KCNK3 is expressed in the heart, lung, brain, liver, kidney, and skeletal muscle. Diseases associated with KCNK3 include Pulmonary Hypertension Primary 4 and Heritable Pulmonary Arterial Hypertension.
Purified by Protein A chromatography
Kcnk3 Task Task1
Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1 (accession number O54192) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
Does not cross-react with TASK3
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1)