Anti-Synaptotagmin-12 Antibody FL490 Conjugate (N277/7)

Name: Anti-Synaptotagmin-12 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-304-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Synaptotagmin-12 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N277/7. It detects mouse and rat Synaptotagmin-12, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-304-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Synaptotagmin-12

Target Description

Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 12 differs from classical synaptotagmins in that it does not bind Ca(2+). In synaptic vesicles, synaptotagmin-12 forms a complex with synaptotagmin-1 that prevents synaptotagmin-1 from interacting with SNARE complexes (Maximov A. et al., 2007).

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N277/7

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Syt12

Molecular Weight

45 kDa (plus others)

Antigen

Fusion protein amino acids 168-255 (cytoplasmic C2A domain) of mouse Synaptotagmin-12 (also known as Syt12, Synaptotagmin XII, SytXII, Synaptotagmin-related gene 1 protein, Srg1 and Sytr1, accession number Q920N7) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940060

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Synaptotagmin-6 (or other Synaptotagmins)

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Synaptotagmin-12 (Synaptotagmin XII) (SytXII)

UniProt Details

UniProt (Human): Q8IV01
UniProt (Immunogen Species): Q920N7

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Anti-Synaptotagmin-12 Antibody FL490 Conjugate (N277/7)

SKU: 75-304-FL490

Product Details

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