Anti-Synaptotagmin-12 Antibody FL550 Conjugate (N277/7)

Name: Anti-Synaptotagmin-12 Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-304-FL550
Price: 486.0 USD
Availability: InStock

Our mouse Synaptotagmin-12 FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N277/7. It detects mouse and rat Synaptotagmin-12 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Synaptotagmin-12 Antibody FL550 Conjugate

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Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-304-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Synaptotagmin-12

Scientific Background

Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 12 differs from classical synaptotagmins in that it does not bind Ca(2+). In synaptic vesicles, synaptotagmin-12 forms a complex with synaptotagmin-1 that prevents synaptotagmin-1 from interacting with SNARE complexes (Maximov A. et al., 2007).

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N277/7

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Syt12

Molecular Weight

45 kDa (plus others)

Immunogen

Fusion protein amino acids 168-255 (cytoplasmic C2A domain) of mouse Synaptotagmin-12 (also known as Syt12, Synaptotagmin XII, SytXII, Synaptotagmin-related gene 1 protein, Srg1 and Sytr1, accession number Q920N7) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940061

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Does not cross-react with Synaptotagmin-6 (or other Synaptotagmins)

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Synaptotagmin-12 (Synaptotagmin XII) (SytXII)

UniProt ID

Q920N7

Shipping

Shipped on ice packs

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Anti-Synaptotagmin-12 Antibody FL550 Conjugate (N277/7)

SKU: 75-304-FL550

Product Details

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