Anti-CALB1/calbindin Antibody Biotin Conjugate (L109/57)

Name: Anti-CALB1/calbindin Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-448-BTN
Price: 543.0 USD
Availability: InStock

Our mouse CALB1/calbindin biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone L109/57. It detects human, mouse, and rat CALB1/calbindin and is purified by Protein A chromatography. Works in ELISA, IHC, ICC, WB.

Anti-CALB1/calbindin Antibody Biotin Conjugate

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

AT, ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

Go to Full Product Details

Data Sheet

SKU: 75-448-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

CALB1/calbindin

Scientific Background

Calbindin (aka. calbindin D28k) is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. It is predominantly expressed in certain types of neurons, particularly in dendrites and perikarya of the cerebellum and is thought to buffer entry of calcium upon stimulation of glutamate receptors (Andressen et al., 1993). Calbindin has recently been shown to play a critical role in mitochondrial dysfunction and loss of synaptic proteins in vivo in an Alzheimer’s disease mouse model (Kook et al., 2014).

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

L109/57

Isotype

IgG1

Applications

AT, ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

CALB1 CAB27

Molecular Weight

30 kDa

Immunogen

Fusion Protein Amino acids 1-261 (full-length) of human CALB1 (accession number P05937) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

avian-type antibody; Calbindin; CAB27 antibody; Calbindin D28; CALB 1 antibody; D-28K; CALB antibody; Vitamin D-dependent calcium-binding protein; CALB1 antibody; CALB1_HUMAN antibody; Calbindin 1 28kDa antibody; Calbindin antibody; Calbindin D28 antibody; D 28K antibody; D-28K antibody; D28K antibody; OTTHUMP00000166027 antibody; OTTHUMP00000225441 antibody; RTVL H protein antibody; Vitamin D dependent calcium binding protein antibody; Vitamin D dependent calcium binding protein avian type antibody; Vitamin D-dependent calcium-binding protein antibody; avian-type

UniProt ID

P05937
UniProt Summary: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

NCBI Gene ID

793

Shipping

Shipped on ice packs

Recover password

Create my account

Anti-CALB1/calbindin Antibody Biotin Conjugate (L109/57)

SKU: 75-448-BTN

Product Details

Bulk Order Anti-CALB1/calbindin Antibody Biotin Conjugate

Related Products

Recently Viewed