Anti-CALB1/calbindin Antibody FL650 Conjugate (L109/57)
Our Anti-CALB1/calbindin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L109/57. It detects human, mouse, and rat CALB1/calbindin, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
SKU: 75-448-FL650
Product Details
CALB1/calbindin
Calbindin (aka. calbindin D28k) is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. It is predominantly expressed in certain types of neurons, particularly in dendrites and perikarya of the cerebellum and is thought to buffer entry of calcium upon stimulation of glutamate receptors (Andressen et al., 1993). Calbindin has recently been shown to play a critical role in mitochondrial dysfunction and loss of synaptic proteins in vivo in an Alzheimer’s disease mouse model (Kook et al., 2014).
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
L109/57
IgG1
ICC, IHC
Mouse
CALB1 CAB27
30 kDa
Fusion protein amino acids 1-261 (full-length) of human CALB1 (accession number P05937) produced recombinantly in E. Coli
Human, Mouse, Rat
AB_2940491
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Calbindin (Calbindin D28) (D-28K) (Vitamin D-dependent calcium-binding protein, avian-type)
UniProt (Human): P05937
UniProt (Immunogen Species): P05937
UniProt (Immunogen Species): P05937