Anti-CALB1/calbindin Antibody FL490 Conjugate (L109/57)

Name: Anti-CALB1/calbindin Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-448-FL490
Price: 474.0 USD
Availability: InStock

Our Anti-CALB1/calbindin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L109/57. It detects human, mouse, and rat CALB1/calbindin, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-448-FL490

Volume: 200 µL

Variant

Price:

$474.00

Quantity:

Ships: 1-5 business days

Product Details

Target

CALB1/calbindin

Target Description

Calbindin (aka. calbindin D28k) is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. It is predominantly expressed in certain types of neurons, particularly in dendrites and perikarya of the cerebellum and is thought to buffer entry of calcium upon stimulation of glutamate receptors (Andressen et al., 1993). Calbindin has recently been shown to play a critical role in mitochondrial dysfunction and loss of synaptic proteins in vivo in an Alzheimer’s disease mouse model (Kook et al., 2014).

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

L109/57

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

CALB1 CAB27

Molecular Weight

30 kDa

Antigen

Fusion protein amino acids 1-261 (full-length) of human CALB1 (accession number P05937) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940488

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Calbindin (Calbindin D28) (D-28K) (Vitamin D-dependent calcium-binding protein, avian-type)

UniProt ID

P05937

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Anti-CALB1/calbindin Antibody FL490 Conjugate (L109/57)

SKU: 75-448-FL490

Product Details

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