Monoclonal Antibodies

3762 products

Monoclonal antibodies are generated from hybridoma clones and are powerful research tools for analyzing proteins to understand biological and cellular functions.

We have a broad portfolio of monoclonal antibodies, including the NeuroMab line, which was developed in collaboration with the UC Davis – NIH facility. These highly-cited, highly-validated antibodies have been trusted by the neuroscience research community for years. Knockout validation guarantees target specificity and production from hybridoma clones provides batch-to-batch consistency and long-term supply.

Analysis of multiple proteins within the same tissue sample, using immunofluorescence is key to advancing research. To support the multiplexing field we provide fluorescent conjugates which include 490, 550, 594 and 650. Our mouse monoclonal conjugates continue to grow in popularity.

Showing 49 - 72 of 3762 products

Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex with L124/59 (magenta), rabbit mAb PSD-95 (Cell Signaling 3450, green) and Hoechst nuclear stain (blue). The insert shows three consecutive sections through the synapse that is marked with a white box.

Adult rat hippocampus immunohistochemistry.

NeuroMab Anti-Bassoon Antibody

From $137

Immunoblot against brain membranes from adult rat (RBM), Slo2.2 knockout (MBM-Slo2.2 KO) or wild-type (MBM-WT) mice probed with N3/26 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University).

Double immunofluorescence staining revealed the expression of the Slack channel (A,D, in red) in somatostatin positive neurons (B,E, in green). Image from publication CC-BY-4.0. PMID:35359569

NeuroMab Anti-Slo2.2/Slack K+ Channel Antibody

From $142

Immunoblot versus adult rat brain membranes (RBM), and adult mouse hippocampal membranes (MHM) from SAP102 knockout and WT mice (mouse samples courtesy of Dr. Richard Huganir).

NeuroMab Anti-SAP102 Antibody

$337

Immunohistochemistry (IHC) staining of Rhesus macaque brain for astrocyte marker Aldh1L1 using Anti-Aldh1L1 Antibody 75-140 (clone N103/39, 1:3000). Tissue was perfusion fixed with 4% paraformaldehyde and 0.1% glutaraldehyde, then drop-fixed in 4% paraformaldehyde for 24 h. Sections were cut in 60 μm thick coronal sections using a vibrating microtome. Image courtesy of Adriana Galvan (Emory University). Additional experimental details can be found at: pubmed.ncbi.nlm.nih.gov/35202614.

NeuroMab Anti-Aldh1L1 (Blotting) Antibody

From $142

Immunofluorescence of human frontal cortex with K28/74 (green), rabbit Synapsin-1 (red) and DAPI (blue). Twelve images from 100 nm sections (left) were volume-reconstructed via array tomography (31.5 x 34 x 1.2 mm, right). Image courtesy of Nancy O’Rourke, Nafisa Ghori and Stephen Smith (Stanford).

Western blot showing specific labeling of PSD95 (Cat. 75-348) in wild type (WT) and Mir324 KO mouse hippocampus. Image from publication CC-BY-4.0. PMID:38082035

NeuroMab Anti-PSD-95 MAGUK Scaffold Protein Antibody

$394

Immunoblot against crude membranes prepared from whole rat (RBM) and mouse (MBM) brain and human cerebral cortex [HBM(Cx)], cerebellum [HBM(Cb)], and hippocampus [HBM(H)] probed with N52A/42 TC supe.

NeuroMab Anti-Mortalin/GRP75 Antibody

From $142

Immunofluorescence staining of sections from adult GluN2C/NR2C wild-type (WT) and knockout (KO) mouse cerebellum with N422/18 (GluN2C/NR2C, red) and L106/83 (Gephyrin, green) TC supe. Tissue courtesy of Sharon Swanger and Stephen Traynelis (Emory).

NeuroMab Anti-GluN2C/NR2C Antibody

From $142

Adult rat cerebral cortex immunohistochemistry.

Hippocampus immunohistochemistry with antigen retrieval via pepsin pretreatment showing axon initial segment and nodal staining.

NeuroMab Anti-Beta4-Spectrin Antibody

From $142

Array tomography immunofluorescence of Lowicryl-embedded sections from adult mouse cerebellum with L109/57 (red) and DAPI (blue). Left panel is a single 70 nm section imaged with a 20X objective, with a scale bar of 50 µm. Right panel is a MAX projection of 10 serial 70 nm sections imaged with a 63X objective, with a scale bar of 20 µm. Images courtesy of Kristina Micheva (Stanford).

NeuroMab Anti-CALB1/calbindin Antibody

$337

Representative image of 4% paraformaldehyde fixed free-floating mouse cerebellum sections stained with Aves Labs anti-PSD-95 recombinant chicken monoclonal antibody (red, Cat No. 78-028) at 1:1000 dilution and co-stained with anti-Calretinin rabbit polyclonal antibody (green). DAPI nuclear stain (blue) shows cell nuclei. Anti-PSD-95 specifically stains the excitatory synapses in the granular layer of the cerebellum. Image courtesy EnCor Biotechnology.

Formalin fixed, paraffin-embedded rat brain cerebellum region showing staining of PSD-95. The sections were stained with anti-PSD-95 recombinant chicken monoclonal antibody (green) (Cat. 78-028) at 1:500 dilution. The stained sections were mounted with Antibodies Incorporated FluoroshieldTM with DAPI and DABCO mounting medium (Cat. AR-6505). DAPI nuclear stain (blue) shows cell nuclei. Anti-PSD-95 specifically stains the excitatory synapses in the granular layer of the cerebellum. Magnification 100X.

Aves Labs Anti-PSD-95 Recombinant Chicken Chimeric mAb

From $144

Transfected cell immunoblot extracts of COS cells transfected with GFP; GFP-tagged HCN2, FGF11/FHF3 FGF13/FHF2 and BKBeta2; or untagged Kv2.1 plasmid and probed with N86/38 TC supe.

Transfected cell immunofluorescence: COS cells expressing GFP-FHF2A. Blue = Hoechst nuclear stain, Green = GFP, Red = N86/38.

NeuroMab Anti-GFP Antibody

$394

Cultured rat hippocampal neuron immunofluorescence: N23B/49 (Pan-Shank) = red, rabbit anti-PSD-95 = green, merge = yellow (bottom right). Image courtesy of Dr. Albert Hung, Picower Institute, MIT.

NeuroMab Anti-Pan-Shank Antibody

From $137

Adult rat dentate gyrus immunohistochemistry.

NeuroMab Anti-Kv1.3 K+ Channel Antibody

From $142

Immunohistochemistry against hippocampus from adult rats treated with pilocarpine to induce seizures (top) and with saline (bottom).

Immunoblot against crude brain low-speed pellets from untreated adult rats (RBLSP), adult rats treated with kainic acid to induce seizures (RBLSP seiz) and adult rats treated with saline (RBLSP non-seiz) probed with N486/32 (left), N408/62 (middle) and N52A/42 (right) TC supe.

NeuroMab Anti-c-FOS Antibody

$337

NeuroMab Anti-Cav1.2 Ca2+ Channel Antibody

$337

Immunoblot versus crude membranes made from adult rat brain (RBM) or GABABR1 wild-type (WT) or knockout (KO) mice probed with N93A/49 (left) or K89/34 (right) TC supe. Mouse brains courtesy of Martin Gassmann and Bernhard Bettler (University of Basel).

NeuroMab Anti-GABA-B-R1 Antibody

From $142

Adult rat striatum immunohistochemistry.

NeuroMab Anti-Parvalbumin Antibody

$337

Immunoblot on adult mouse brain membranes from two wild-type (WT1,2) and Kvβ2 knockout (Kvβ2 KO) mice. Brain samples courtesy of Dr. Geoff Murphy, Molecular and Behavioral Neuroscience Institute, University of Michigan.

NeuroMab Anti-Kvbeta2 K+ Channel Antibody

$337

Western blotting of rat brain homogenate (10 ug/lane) with anti-GAD65/67 (L127/12) at 1:100 dilution and detected with anti-mouse HRP.

Confocal images of immunostained rat dendritic section of hippocampal neurons labeled with GAD65 (Cat. 75-508, 1:100, blue), total NL2 (red), and synaptic NL2 (green). Neurons were overexpressing SNX27GFPWT (B), SNX27GFPH112A (C), or mock transfected (A, control). Image from publication CC-BY-4.0. PMID 31775031

NeuroMab Anti-GAD65/67 Antibody

$337

Immunolabeling of postnatal 14 mouse CA3 specifically labeling PSD93 (Cat. 75-057, 1:400, green) and Ankyrin G(red). DNA labeled with DAPI. Mice were transcardially perfused with ice-cold 4% paraformaldehyde in PBS, then brain removed and postfixed overnight. The 50uM slices were floating sections. Objective 25x, scale bar = 20um. Images kindly provided by Jorge Ramirez-Franco and Oussama El Far, Aix-Marseille Université and INSERM.

Immunoblot against crude membranes from whole adult rat brain (RBM) or hippocampi (MHM) from adult PSD-93/Chapsyn-110 knockout (KO) or wild-type (WT) mice. Mouse samples courtesy of Richard Huganir (Johns Hopkins University).

NeuroMab Anti-Chapsyn-110/PSD-93 Antibody

$337

Transfected cell immunoblot: extracts of COS cells transiently transfected with Flag-tagged Neurexin-1-Alpha, Neurexin-1- Beta or untagged Kv2.1 plasmid and probed with N170A/1 TC supe (left) and rabbit anti-Flag (right).

NeuroMab Anti-Neurexin-1-Beta (Staining) Antibody

From $142

Adult rat whole brain immunohistochemistry

NeuroMab Anti-GABA-A-R-Beta2/3 Antibody

$337

Double-labeled fluorescence immunohistochemistry of human midbrain dopamine neurons stained green with LNC1 and red with PitX.

Western Blot of HEK293 cells transfected to express human Tyrosine Hydroxylase isoform 2 and Green Fluorescent Protein demonstrates the specificity of mouse monoclonal antibody LNC1 to tyrosine hydroxylase protein.

Antibodies Incorporated Anti-Tyrosine Hydroxylase Antibody (Purified)

From $142

Distribution of SHANK3 immuno-positive cells in different regions of the adult mouse cerebral cortex. N, O: High-magnification views of SHANK3-positive cells in the RSPV region (N) and hippocampal region (O) as shown in image M. Green, SHANK3-positive cells (Cat. 75-344, 1:200); blue, cell nuclei. Scale bars, 300 μm (M); 100 μm (N, O). Image from publication, CC-BY-4.0. PMID: 39693031.

Adult rat hippocampus immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

NeuroMab Anti-Shank3 Antibody

$394

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Monoclonal Antibodies

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