Products: Primary Antibodies

Anti-TrpM6 Antibody (N470/22)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-464
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-464
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2a

Species Reactivity:

Human

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

WB

Target Description:

Transient receptor potential cation channel subfamily M member 6 or TrpM6 is encoded by the gene TRPM6. TrpM6 is a member of the transient receptor potential ion channel family and acts as a serine/threonine-protein kinase. TrpM6 has an essential function in magnesium transport and is involved with magnesium absorption in the gut and kidney. TRPM6 is primarily expressed in the kidney, colon, GI tract and placenta kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia.

Immunogen:

Fusion protein amino acids 1258-1480 (cytoplasmic C-terminus) of human TrpM6 (also known as Transient receptor potential cation channel subfamily M member 6, Melastatin-related TRP cation channel 6, Channel kinase 2 and CHAK2, accession number Q9BX84)

Protein Name(s):

TrpM6 (Transient receptor potential cation channel subfamily M member 6) (Melastatin-related TRP cation channel 6) (Channel kinase 2)

Gene Name(s):

TRPM6 CHAK2

Antibody Registry ID:

Purified: AB_2714206
TC Supernatant: AB_2631244


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

240 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.