Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (N165/43)

Name: Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody
Brand: NeuroMab
SKU: 75-194
Price: 319.0 USD
Availability: InStock

1 Citation

Our Anti-Pan-PTPR (Receptor-type tyrosine-protein phosphatase) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N165/43. It detects human, mouse, and rat Pan-PTPR (Receptor-type tyrosine-protein phosphatase), and is purified by Protein A chromatography. It is great for use in ICC, WB.

Adult rat brain membrane immunoblot.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-194

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Pan-PTPR (Receptor-type tyrosine-protein phosphatase)

Target Description

This is pan and reacts with PTPRF, Protein Tyrosine Phosphatase Receptor Type D (PTPRD) or Protein Tyrosine Phosphatase Receptor Type S (PTPRS) which are all members of the protein tyrosine phosphatase (PTP) family. These proteins are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N165/43

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

PTPRF LAR PTPRD PTPRS

Molecular Weight

85 kDa (full-length is 210 kDa, smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains)

Antigen

Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR (accession number P10586) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2174700

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.122

Conjugate

Unconjugated

Specificity

Cross-reacts with PTPRD or PTPRS

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)

UniProt Details

UniProt (Human): P10586
UniProt (Immunogen Species): P10586

Kuhn PH, Koroniak K, Hogl S, Colombo A, Zeitschel U, Willem M, Volbracht C, Schepers U, Imhof A, Hoffmeister A, Haass C, Roßner S, Bräse S, Lichtenthaler SF. (2012), 'Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons..' The EMBO Journal. 10.1038/emboj.2012.173.

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Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (N165/43)

SKU: 75-194

Product Details

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