Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (BSA and Azide free) (N165/43)

Name: Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-194-CF
Price: 486.0 USD
Availability: InStock

Our mouse Pan-PTPR (Receptor-type tyrosine-protein phosphatase) carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N165/43. It detects human, mouse, and rat Pan-PTPR (Receptor-type tyrosine-protein phosphatase) and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

SKU: 75-194-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Pan-PTPR (Receptor-type tyrosine-protein phosphatase)

Scientific Background

This is pan and reacts with PTPRF, Protein Tyrosine Phosphatase Receptor Type D (PTPRD) or Protein Tyrosine Phosphatase Receptor Type S (PTPRS) which are all members of the protein tyrosine phosphatase (PTP) family. These proteins are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N165/43

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

PTPRF LAR PTPRD PTPRS

Molecular Weight

85 kDa (full-length is 210 kDa, smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains)

Immunogen

Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR (accession number P10586) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Cross-reacts with PTPRD or PTPRS

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

BNAH2; Receptor-type tyrosine-protein phosphatase F; EC 3.1.3.48; LCA-homolog; Leukocyte common antigen related; leukocyte antigen-related (LAR PTP receptor; LAR Receptor-type tyrosine-protein phosphatase delta; leukocyte antigen-related tyrosine phosphatase; Protein-tyrosine phosphatase delta; R-PTP-delta; receptor-linked protein-tyrosine phosphatase LAR; EC 3.1.3.48 Receptor-type tyrosine-protein phosphatase S; R-PTP-S; Receptor-type tyrosine-protein phosphatase sigma; R-PTP-sigma

UniProt ID

P10586
UniProt Summary: Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.; The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.

NCBI Gene ID

5792

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Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (BSA and Azide free) (N165/43)

SKU: 75-194-CF

Product Details

Bulk Order Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (BSA and Azide free)

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