Products: Primary Antibodies

Anti-Neuregulin-CRD (Cysteine-rich domain, Type III) Antibody (N126B/31)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-226
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-226
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2b

Species Reactivity:

Human Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC WB

Target Description:

Neuregulin 1 is encoded by the gene NRG1. NRG1 is a member of the neuregulin family. NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. NRG1 is expressed in the nervous system, intestine, muscle, and heart. Diseases associated with NRG1 include Schizphrenia 6 and Lung Cancer.

Immunogen:

Fusion protein amino acids 1-75 (membrane-associated N-terminus) of human Neuregulin-1 (also known as NRG1, Neu differentiation factor, NDF, Heregulin, HRG, HGL, Breast cancer cell differentiation factor p45, Acetylcholine receptor-inducing activity, ARIA, Glial growth factor, GGF, Sensory and motor-neuron-derived factor or SMDF, accession number Q96IB3); Mouse: 85% identity (64/75 amino acids identical); Rat: 82% identity (63/76 amino acids identical)

Cross Reactivity:

No cross-reactivity reported

Protein Name(s):

Neuregulin-CRD (Cysteine-rich domain, Type III)

Gene Name(s):

NRG1

Antibody Registry ID:

Purified: AB_10672367
TC Supernatant: AB_10672412


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

30 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.