Anti-GABA-B-R1 Antibody (N93A/49)

Our Anti-GABA(B)R1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N93A/49. It is KO validated, detects human and mouse GABA(B)R1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.



SKU: 75-183

Volume: 100 µL
1-2 business days
Price:
Sale price$319

Product Specific References for Applications and Species

dSTORM: Mouse
PMID Dilution Publication
338887181:1000Fujun, L., et al. 2021. Neurexins regulate presynaptic GABAB-receptors at central synapses. Nature Communications, 2380.
Immunocytochemistry: Mouse
PMID Dilution Publication
36395772not listedKleinjan, M.S., et al. 2023. Dually Innervated Dendritic Spines Develop In The Absence Of Excitatory Activity And Resist Plasticity Through Tonic Inhibitory Crosstalk. Neuron, 362-371.
Immunocytochemistry: Rat
PMID Dilution Publication
286602461:50Li, P., et al. 2017. GABA-B controls persistent Na+ current and coupled Na+-activated K+ current. eNeuro, .
262123831 : 15Karls, A., et al. 2015. GABA(B) receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development.. Journal of Neurochemistry, 88-100.
Immunohistochemistry: Chicken
PMID Dilution Publication
262986281:8 (supe)Frederikse, P.H., et al. 2015. Fragile X Syndrome FMRP Co-localizes with Regulatory Targets PSD-95, GABA Receptors, CaMKIIα, and mGluR5 at Fiber Cell Membranes in the Eye Lens.. Neurochemical Research, 2167-2176.
Immunohistochemistry: Mouse
PMID Dilution Publication
338887181:500Fujun, L., et al. 2021. Neurexins regulate presynaptic GABAB-receptors at central synapses. Nature Communications, 2380.
319150421:500Rice, H.C., et al. 2020. Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model. Molecular Neurodengeneration, 3.
213368281:100Broussard, D.M., et al. 2011. Motor learning in the VOR: the cerebellar component.. Experimental Brain Research, 451-463.
Immunohistochemistry: rabbit
PMID Dilution Publication
26539026not listedFrederikse, P.H., et al. 2015. KCC2 expression supersedes NKCC1 in mature fiber cells in mouse and rabbit lenses.. Molecular Vision, 1142-1150.
262986281:8 (supe)Frederikse, P.H., et al. 2015. Fragile X Syndrome FMRP Co-localizes with Regulatory Targets PSD-95, GABA Receptors, CaMKIIα, and mGluR5 at Fiber Cell Membranes in the Eye Lens.. Neurochemical Research, 2167-2176.
Immunohistochemistry: Rat
PMID Dilution Publication
230976971:500Kramer, A.A., et al. 2012. Levels of Ca(V)1.2 L-Type Ca(2+) Channels Peak in the First Two Weeks in Rat Hippocampus Whereas Ca(V)1.3 Channels Steadily Increase through Development.. Journal of Signal Transduction, 597214.
Immuno Gold Pre/Post Embedd: Mouse
PMID Dilution Publication
3424850810ug/mlRoldán-Sastre, A., et al. 2021. Cellular Diversity and Differential Subcellular Localization of the G-Protein Gαo Subunit in the Mouse Cerebellum. Frontiers of Neuroanatomy, 686279.
268083471-2ug/mlLecca, S., et al. 2016. Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice. Nature Medicine, 254-261.
22405207not listedPadgett, C.L., et al. 2012. Methamphetamine-evoked depression of GABA(B) receptor signaling in GABA neurons of the VTA.. Neuron, 978-989.
PLA: Mouse
PMID Dilution Publication
275732461:100Zemoura, K., et al. 2016. Lys-63-linked ubiquitination of γ-aminobutyric acid (GABA), type B1, at multiple sites by the E3 ligase mind bomb-2 targets GABAB receptors to lysosomal …. Journal of Biological Chemistry, 21682-21693.
PLA: Rat
PMID Dilution Publication
32111696not listedBurke, J.F., et al. 2020. Direct interaction of PP2A phosphatase with GABAB receptors alters functional signaling. Journal of Neuroscience, 2808-2816.
298819491:50Zemoura, K., et al. 2019. Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) β-Dependent Phosphorylation of GABAB1 Triggers Lysosomal Degradation of GABAB Receptors via Mind Bomb-2 (MIB2)-Mediated Lys-63-Linked Ubiquitination. Molecular Neurobiology, 1293-1309.
Western Blot: Mouse
PMID Dilution Publication
25172509not listedHuyghe, D., et al. 2014. Glutamine synthetase stability and subcellular distribution in astrocytes are regulated by γ-aminobutyric type B receptors. . Journal of Biological Chemistry, 28808-28815.
24431439not listedTerunuma, M., et al. 2014. Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory.. Journal of Neuroscience, 804-816.
222077611:200Schwindinger, W.F., et al. 2012. Synergistic roles for G-protein γ3 and γ7 subtypes in seizure susceptibility as revealed in double knock-out mice.. The Journal of Biological Chemistry, 7121-7133.
216366561:250Pacey, L.K., et al. 2011. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome.. Journal of Pharmacology and Experimental Therapeutics, 897-905.
Western Blot: Rat
PMID Dilution Publication
28450542not listedWright, R., et al. 2017. Neuronal chloride regulation via KCC2 is modulated through a GABAB receptor protein complex. . Journal of Neuroscience, 5447-5462.
26691831not listedSchwenk, J., et al. 2016. Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics.. Nature Neuroscience, 233-242.
Additional Publications: Unspecified
PMID Publication
21215802Pacey, L.K., et al. 2011. Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse.. Molecular and Cellular Neuroscience, 563-572.

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