Anti-Slo1 Maxi-K+ Channel Antibody FL594 Conjugate (L6/60)

Name: Anti-Slo1 Maxi-K+ Channel Antibody FL594 Conjugate
Brand: NeuroMab
SKU: 75-022-FL594
Price: 515.0 USD
Availability: InStock

Our Anti-Slo1 maxi-K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L6/60. It is KO validated, detects human, mouse, rat, sheep, and zebrafish Slo1 maxi-K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat, Sheep, Zebrafish

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

550

650

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Data Sheet

KO Validated

SKU: 75-022-FL594

Volume: 200 µL

Variant

Price:

$515.00

Quantity:

Product Details

Target

Slo1 maxi-K+ channel

Target Description

mSlo maxi K+ channel (Calcium-activated potassium channel subunit alpha-1) is a member of BK channel alpha subunit family and has the particularity to be regulated by both Ca2+ and membrane depolarization.BK channels have a tetrameric structure. Each subunit is the product of the KCNMA1 gene. All modulatory subunits encoded by KCNMB1, KCNMB2, KCNMB3, or KCNMB4 can associate with the tetrameric channel. MSlo plays a major role in controlling cell excitability, which regulates smooth muscle contractions, transmitter release, and innate immune system cell activation. MSlo maxi-K+ channel contributes to repolarization of the membrane potential as it exports K+ out of the cytosol.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

L6/60

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnma1 Kcnma

Molecular Weight

110-130 kDa

Antigen

Fusion protein amino acids 690-1196 (cytoplasmic C-terminus) of mouse Slo1 (accession number AAA39746) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat, Sheep, Zebrafish

Antibody Registry ID

AB_2939150

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (mSlo1) (Slowpoke homolog) (Slo homolog) (mSlo)

UniProt Details

UniProt (Human): Q12791
UniProt (Immunogen Species): Q08460-2

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Anti-Slo1 Maxi-K+ Channel Antibody FL594 Conjugate (L6/60)

SKU: 75-022-FL594

Product Details

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