Bulk Order Anti-Slo1 Maxi-K+ Channel Antibody FL594 Conjugate
Slo1 maxi-K+ channel
mSlo maxi K+ channel (Calcium-activated potassium channel subunit alpha-1) is a member of BK channel alpha subunit family and has the particularity to be regulated by both Ca2+ and membrane depolarization.BK channels have a tetrameric structure. Each subunit is the product of the KCNMA1 gene. All modulatory subunits encoded by KCNMB1, KCNMB2, KCNMB3, or KCNMB4 can associate with the tetrameric channel. MSlo plays a major role in controlling cell excitability, which regulates smooth muscle contractions, transmitter release, and innate immune system cell activation. MSlo maxi-K+ channel contributes to repolarization of the membrane potential as it exports K+ out of the cytosol.
Purified by Protein A chromatography
Fusion protein amino acids 690-1196 (cytoplasmic C-terminus) of mouse Slo1 (accession number AAA39746) produced recombinantly in E. Coli
Human, Mouse, Rat, Sheep, Zebrafish
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.