Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate (L6/60)

Name: Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-022-FL550
Price: 499.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

490

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat, Sheep, Zebrafish

Clone

L6/60

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Kcnma1 Kcnma

Molecular Weight

110-130 kDa

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Volume: 200 µL

Variant

Price:

$499

Quantity:

Bulk Order Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate

Product Details

Target

Slo1 maxi-K+ channel

Target Description

mSlo maxi K+ channel (Calcium-activated potassium channel subunit alpha-1) is a member of BK channel alpha subunit family and has the particularity to be regulated by both Ca2+ and membrane depolarization.BK channels have a tetrameric structure. Each subunit is the product of the KCNMA1 gene. All modulatory subunits encoded by KCNMB1, KCNMB2, KCNMB3, or KCNMB4 can associate with the tetrameric channel. MSlo plays a major role in controlling cell excitability, which regulates smooth muscle contractions, transmitter release, and innate immune system cell activation. MSlo maxi-K+ channel contributes to repolarization of the membrane potential as it exports K+ out of the cytosol.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

L6/60

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnma1 Kcnma

Molecular Weight

110-130 kDa

Antigen

Fusion protein amino acids 690-1196 (cytoplasmic C-terminus) of mouse Slo1 (accession number AAA39746) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat, Sheep, Zebrafish

Antibody Registry ID

AB_2939149

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (mSlo1) (Slowpoke homolog) (Slo homolog) (mSlo)

UniProt Details

UniProt (Human): Q12791
UniProt (Immunogen Species): Q08460-2

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Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate (L6/60)

Available Conjugates

Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate
SKU: 75-022-FL550

Bulk Order Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate

Product Details

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Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate (L6/60)

Available Conjugates

Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate SKU: 75-022-FL550

Bulk Order Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate

Product Details

Anti-Slo1 Maxi-K+ Channel Antibody FL550 Conjugate
SKU: 75-022-FL550