Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (N165/43)

Name: Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody
Brand: NeuroMab
SKU: 75-194
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N165/43

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

PTPRF LAR PTPRD PTPRS

Molecular Weight

85 kDa(full-length is 210 kDa, smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains)

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Adult rat brain membrane immunoblot.

Volume: 100 µL

Variant

Price:

$308

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Bulk Order Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody

Product Details

Target

Pan-PTPR (Receptor-type tyrosine-protein phosphatase)

Target Description

This is pan and reacts with PTPRF, Protein Tyrosine Phosphatase Receptor Type D (PTPRD) or Protein Tyrosine Phosphatase Receptor Type S (PTPRS) which are all members of the protein tyrosine phosphatase (PTP) family. These proteins are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N165/43

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

PTPRF LAR PTPRD PTPRS

Molecular Weight

85 kDa(full-length is 210 kDa, smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains)

Antigen

Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR (also known as Leukocyte antigen related, Leukocyte common antigen-related phosphatase, Receptor-type tyrosine-protein phosphatase F and PTPRF, accession number P10586); Rat: 97% identity (286/293 amino acids identical); Mouse: 97% identity (285/293 amino acids identical); Greater than 80% identity with PTPRD and PTPRS; Greater than 50% identity with PTPRM and PTPRK

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2174700

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Cross-reacts with PTPRD or PTPRS

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)

Kuhn PH, Koroniak K, Hogl S, Colombo A, Zeitschel U, Willem M, Volbracht C, Schepers U, Imhof A, Hoffmeister A, Haass C, Roßner S, Bräse S, Lichtenthaler SF. (2012), 'Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons..' The EMBO Journal. 10.1038/emboj.2012.173.

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Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (N165/43)

Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody
SKU: 75-194

Bulk Order Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody

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Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (N165/43)

Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody SKU: 75-194

Bulk Order Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody

Product Details

Anti-Pan-PTPR (Receptor-Type Tyrosine-Protein Phosphatase) Antibody
SKU: 75-194