Anti-Pan-GRK FL594 Conjugate (N145/20)
Our Anti-Pan-GRK mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N145/20. It detects human, mouse, and rat Pan-GRK, and is purified by Protein A chromatography. It is great for use in ICC.
SKU: 75-179-FL594
Product Details
Pan-GRK
G protein-coupled receptor (GPCR) kinases (GRKs), are important regulators of GPCR function and mediate receptor desensitization, internalization, and signaling. Several non-GPCR proteins also serve as GRK substrates, and GRKs have been shown to have kinase-independent functions through regulation of receptors and effectors. These proteins are members of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. GRKs phosphorylate activated forms of G protein-coupled receptors to regulate their signaling.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N145/20
IgG1
ICC
Mouse
Grk5 Gprk5 Grk6 Gprk6
70 kDa
Fusion protein amino acids 381-590 (C-terminus) of mouse GRK5 (accession number Q8VEB1) produced recombinantly in E. Coli
Human, Mouse, Rat
AB_2939662
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
Cross-reacts with GRK6
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)
UniProt (Human): P34947
UniProt (Immunogen Species): Q8VEB1
UniProt (Immunogen Species): Q8VEB1