Primary Antibody
Human, Mouse, Rat
K87A/10
IHC, IP
Mouse
Purified
Scn8a
<200 kDa
- Jones JM, Dionne L, Dell''Orco J, Parent R, Krueger JN, Cheng X, Dib-Hajj SD, Bunton-Stasyshyn RK, Sharkey LM, Dowling JJ, Murphy GG, Shakkottai VG, Shrager P, Meisler MH. (2016), 'Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder..' Neurobiology of Disease. 10.1016/j.nbd.2016.01.018.
- Barbosa C, Tan ZY, Wang R, Xie W, Strong JA, Patel RR, Vasko MR, Zhang JM, Cummins TR. (2015), 'Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons..' Molecular Pain. 10.1186/s12990-015-0063-9.
- Brügger V, Engler S, Pereira JA, Ruff S, Horn M, Welzl H, Münger E, Vaquié A, Sidiropoulos PN, Egger B, Yotovski P, Filgueira L, Somandin C, Lühmann TC, D''Antonio M, Yamaguchi T, Matthias P, Suter U, Jacob C. (2015), 'HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins..' PLoS Biology. 10.1371/journal.pbio.1002258.
- Hirono M, Ogawa Y, Misono K, Zollinger DR, Trimmer JS, Rasband MN, Misonou H. (2015), 'BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells..' Journal of Neuroscience. 10.1523/JNEUROSCI.3778-14.2015.
- Baalman K, Marin MA, Ho TS, Godoy M, Cherian L, Robertson C, Rasband MN. (2015), 'Axon initial segment-associated microglia..' Journal of Neuroscience. 10.1523/JNEUROSCI.3751-14.2015.
- Wimmer VC, Harty RC, Richards KL, Phillips AM, Miyazaki H, Nukina N, Petrou S. (2015), 'Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain..' Journal of Comparative Neurology. 10.1002/cne.23715.
- Chang KJ, Zollinger DR, Susuki K, Sherman DL, Makara MA, Brophy PJ, Cooper EC, Bennett V, Mohler PJ, Rasband MN. (2014), 'Glial ankyrins facilitate paranodal axoglial junction assembly..' Nature Neuroscience. 10.1038/nn.3858.
- King AN, Manning CF, Trimmer JS. (2014), 'A unique ion channel clustering domain on the axon initial segment of mammalian neurons..' Journal of Comparative Neurology. 10.1002/cne.23551.
- Xiao M, Bosch MK, Nerbonne JM, Ornitz DM. (2013), 'FGF14 localization and organization of the axon initial segment..' Molecular and Cellular Neuroscience. 10.1016/j.mcn.2013.07.008.
- Ruff CA, Ye H, Legasto JM, Stribbell NA, Wang J, Zhang L, Fehlings MG. (2013), 'Effects of adult neural precursor-derived myelination on axonal function in the perinatal congenitally dysmyelinated brain: optimizing time of intervention, developing accurate prediction models, and enhancing performance..' Journal of Neuroscience. 10.1523/JNEUROSCI.1131-13.2013.
- Sun W, Wagnon JL, Mahaffey CL, Briese M, Ule J, Frankel WN. (2013), 'Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice..' The Journal of Physiology. 10.1113/jphysiol.2012.240168.
- Baalman KL, Cotton RJ, Rasband SN, Rasband MN. (2013), 'Blast wave exposure impairs memory and decreases axon initial segment length..' Journal of Neurotrauma. 10.1089/neu.2012.2478.
- Devaux JJ. (2012), 'Antibodies to gliomedin cause peripheral demyelinating neuropathy and the dismantling of the nodes of Ranvier..' The American Journal of Pathology. 10.1016/j.ajpath.2012.06.034.
- Buttermore ED, Piochon C, Wallace ML, Philpot BD, Hansel C, Bhat MA. (2012), 'Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal development..' Journal of Neuroscience. 10.1523/JNEUROSCI.5602-11.2012.
- Shepherd MN, Pomicter AD, Velazco CS, Henderson SC, Dupree JL. (2012), 'Paranodal reorganization results in the depletion of transverse bands in the aged central nervous system..' Neurobiology of Aging. 10.1016/j.neurobiolaging.2010.08.001.
- Duflocq A, Chareyre F, Giovannini M, Couraud F, Davenne M. (2011), 'Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B..' BMC Biology. 10.1186/1741-7007-9-66.
- Meehan CF, MacDermid VE, Montague SJ, Neuber-Hess M, Rose PK. (2011), 'Dendrite-derived supernumerary axons on adult axotomized motor neurons possess proteins that are essential for the initiation and propagation of action potentials and synaptic vesicle release..' Journal of Neuroscience. 10.1523/JNEUROSCI.5377-10.2011.
- Binder E, Rukavina M, Hassani H, Weber M, Nakatani H, Reiff T, Parras C, Taylor V, Rohrer H. (2011), 'Peripheral nervous system progenitors can be reprogrammed to produce myelinating oligodendrocytes and repair brain lesions..' Journal of Neuroscience. 10.1523/JNEUROSCI.0129-11.2011.
- Tong M, Hernandez JL, Purcell EK, Altschuler RA, Duncan RK. (2010), 'The intrinsic electrophysiological properties of neurons derived from mouse embryonic stem cells overexpressing neurogenin-1..' American Journal of Physiology-Cell Physiology. 10.1152/ajpcell.00207.2010.
- Crawford DK, Mangiardi M, Song B, Patel R, Du S, Sofroniew MV, Voskuhl RR, Tiwari-Woodruff SK. (2010), 'Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination..' Brain. 10.1093/brain/awq237.
- Howell OW, Rundle JL, Garg A, Komada M, Brophy PJ, Reynolds R. (2010), 'Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis..' Journal of Neuropathology & Experimental Neurology. 10.1097/NEN.0b013e3181f3a5b1.
- Wimmer VC, Reid CA, Mitchell S, Richards KL, Scaf BB, Leaw BT, Hill EL, Royeck M, Horstmann MT, Cromer BA, Davies PJ, Xu R, Lerche H, Berkovic SF, Beck H, Petrou S. (2010), 'Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus..' Journal of Clinical Investigation. 10.1172/JCI42219.
- Lorincz A, Nusser Z. (2010), 'Molecular identity of dendritic voltage-gated sodium channels..' Science. 10.1126/science.1187958.
- Wimmer VC, Reid CA, So EY, Berkovic SF, Petrou S. (2010), 'Axon initial segment dysfunction in epilepsy..' The Journal of Physiology. 10.1113/jphysiol.2010.188417.
- Liao Y, Deprez L, Maljevic S, Pitsch J, Claes L, Hristova D, Jordanova A, Ala-Mello S, Bellan-Koch A, Blazevic D, Schubert S, Thomas EA, Petrou S, Becker AJ, De Jonghe P, Lerche H. (2010), 'Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy..' Brain. 10.1093/brain/awq057.
- Osorio N, Cathala L, Meisler MH, Crest M, Magistretti J, Delmas P. (2010), 'Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells..' The Journal of Physiology. 10.1113/jphysiol.2010.183798.
- Brackenbury WJ, Calhoun JD, Chen C, Miyazaki H, Nukina N, Oyama F, Ranscht B, Isom LL. (2010), 'Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth..' Proceedings of the National Academy of Science of the United States of America. 10.1073/pnas.0909434107.
- Crawford DK, Mangiardi M, Xia X, López-Valdés HE, Tiwari-Woodruff SK. (2009), 'Functional recovery of callosal axons following demyelination: a critical window..' Neuroscience. 10.1016/j.neuroscience.2009.09.069.
- Sharkey LM, Cheng X, Drews V, Buchner DA, Jones JM, Justice MJ, Waxman SG, Dib-Hajj SD, Meisler MH. (2009), 'The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking..' Journal of Neuroscience. 10.1523/JNEUROSCI.6026-08.2009.
- O''Malley HA, Shreiner AB, Chen GH, Huffnagle GB, Isom LL. (2009), 'Loss of Na+ channel beta2 subunits is neuroprotective in a mouse model of multiple sclerosis..' Molecular and Cellular Neuroscience. 10.1016/j.mcn.2008.10.001.
- Lorincz A, Nusser Z. (2008), 'Cell-type-dependent molecular composition of the axon initial segment..' Journal of Neuroscience. 10.1523/JNEUROSCI.4833-08.2008.
- Shakkottai VG, Xiao M, Xu L, Wong M, Nerbonne JM, Ornitz DM, Yamada KA. (2008), 'FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons..' Neurobiology of Disease. 10.1016/j.nbd.2008.09.019.
- Mojumder DK, Wensel TG, Frishman LJ. (2008), 'Subcellular compartmentalization of two calcium binding proteins, calretinin and calbindin-28 kDa, in ganglion and amacrine cells of the rat retina..' Molecular Vision. .
- Duflocq A, Le Bras B, Bullier E, Couraud F, Davenne M. (2008), 'Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments..' Molecular and Cellular Neuroscience. 10.1016/j.mcn.2008.06.008.
- Windrem MS, Schanz SJ, Guo M, Tian GF, Washco V, Stanwood N, Rasband M, Roy NS, Nedergaard M, Havton LA, Wang S, Goldman SA. (2008), 'Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse..' Cell Stem Cell. 10.1016/j.stem.2008.03.020.
- Mojumder DK, Frishman LJ, Otteson DC, Sherry DM. (2007), 'Voltage-gated sodium channel alpha-subunits Na(v)1.1, Na(v)1.2, and Na(v)1.6 in the distal mammalian retina..' Molecular Vision. .
- Lopez-Santiago LF, Pertin M, Morisod X, Chen C, Hong S, Wiley J, Decosterd I, Isom LL. (2006), 'Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain..' Journal of Neuroscience. 10.1523/JNEUROSCI.2211-06.2006.
- Rush AM, Wittmack EK, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG. (2006), 'Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily..' European Journal of Neuroscience. 10.1111/j.1460-9568.2006.04789.x.