Anti-GABA-B-R2 Antibody FL550 Conjugate (N81/37)

Name: Anti-GABA-B-R2 Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-125-FL550
Price: 486.0 USD
Availability: InStock

Our mouse GABA(B)R2 FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N81/37. It detects human, mouse, and rat GABA(B)R2 and is purified by Protein A chromatography. Works in IHC.

Anti-GABA-B-R2 Antibody FL550 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-125-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

GABA(B)R2

Scientific Background

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. It has recently been demonstrated that AMPK binds directly to GABAB receptors.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N81/37

Isotype

IgG1

Applications

IHC

Host Species

Mouse

Gene Name

GABBR2 GPR51 GPRC3B

Molecular Weight

105 kDa

Immunogen

Fusion protein amino acids 861-912 of human GABABR2 (accession number NP_113990) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939465

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity against GABABR1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20)

UniProt ID

O75899

Shipping

Shipped on ice packs

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Anti-GABA-B-R2 Antibody FL550 Conjugate (N81/37)

SKU: 75-125-FL550

Product Details

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