Anti-TrpM6 Antibody (N470/22)

Name: Anti-TrpM6 Antibody
Brand: NeuroMab
SKU: 75-464
Price: 337.0 USD
Availability: InStock

Our mouse TrpM6 monoclonal antibody from NeuroMab is produced in-house from clone N470/22. It detects human TrpM6 and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Immunoblot against extracts of COS cells transiently transfected with HA-tagged TrpM6 or untagged Kv2.1 plasmid probed with N470/22 (left) or rabbit anti-HA (right).

Click on image to zoom

Species Reactivity

Human

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-464

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

TrpM6

Scientific Background

Transient receptor potential cation channel subfamily M member 6 or TrpM6 is encoded by the gene TRPM6. TrpM6 is a member of the transient receptor potential ion channel family and acts as a serine/threonine-protein kinase. TrpM6 has an essential function in magnesium transport and is involved with magnesium absorption in the gut and kidney. TRPM6 is primarily expressed in the kidney, colon, GI tract and placenta kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N470/22

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

TRPM6 CHAK2

Molecular Weight

240 kDa

Immunogen

Fusion protein amino acids 1258-1480 (cytoplasmic C-terminus) of human TrpM6 (accession number Q9BX84) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human

Antibody Registry ID

AB_2714206

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

TrpM6 (Transient receptor potential cation channel subfamily M member 6) (Melastatin-related TRPcation channel 6) (Channel kinase 2)

UniProt ID

Q9BX84

Shipping

Shipped on ice packs

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Anti-TrpM6 Antibody (N470/22)

SKU: 75-464

Product Details

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