Anti-Synaptotagmin-3 Antibody FL490 Conjugate (N278/19)

Name: Anti-Synaptotagmin-3 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-269-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Synaptotagmin-3 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N278/19. It detects human, mouse, and rat Synaptotagmin-3 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Synaptotagmin-3 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-269-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Synaptotagmin-3

Scientific Background

Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 3 is predominantly expressed in postsynaptic endocytic zones of neurons and has recently been shown to internalize AMPA receptors to depress synaptic strength and promote forgetting (Awasthi A. et al., 2019).

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N278/19

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Syt3

Molecular Weight

75 kDa

Immunogen

Fusion protein amino acids 442-533 (cytoplasmic C2B domain) of mouse Synaptotagmin-3 (accession number O35681) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939964

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with other Synaptotagmins

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Synaptotagmin-3 (Synaptotagmin III) (SytIII)

UniProt ID

O35681

Shipping

Shipped on ice packs

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Anti-Synaptotagmin-3 Antibody FL490 Conjugate (N278/19)

SKU: 75-269-FL490

Product Details

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