Anti-Cavbeta4 Ca2+ Channel Antibody FL550 Conjugate (N10/7)

Name: Anti-Cavbeta4 Ca2+ Channel Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-054-FL550
Price: 486.0 USD
Availability: InStock

Our mouse Cavbeta4 Ca2+ channel FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N10/7. It detects human, mouse, pig, and rat Cavbeta4 Ca2+ channel and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Cavbeta4 Ca2+ Channel Antibody FL550 Conjugate

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Species Reactivity

Human, Mouse, Pig, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-054-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Cavbeta4 Ca2+ channel

Scientific Background

Voltage-dependent L-type calcium channel subunit beta-4 or Cav ß4 is encoded by the gene CACNB4. Cavß4 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß4 is expressed predominantly in the brain (cerebellum) and kidney. Diseases associated with this gene include Episodic Ataxia, Type 5 and Epilepsy.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N10/7

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Cacnb4 Cacnlb4

Molecular Weight

50 kDa

Immunogen

Synthetic peptide amino acids 458-474 of rat Cav4 (DENYHNERARKSRNRLS; accession number D4A055)

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Pig, Rat

Antibody Registry ID

AB_2939237

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity against rat Cavβ1b, Cavβ2a, and Cavβ3 in transfected cells

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4)

UniProt ID

D4A055

Shipping

Shipped on ice packs

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Anti-Cavbeta4 Ca2+ Channel Antibody FL550 Conjugate (N10/7)

SKU: 75-054-FL550

Product Details

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