Anti-Cavbeta4 Ca2+ Channel Antibody (N10/7)

Our Anti-Cavbeta4 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N10/7. It detects human, mouse, pig, and rat Cavbeta4 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

SKU: 75-054

Volume: 100 µL
1-2 business days
Sale price$319.00

Product Specific References for Applications and Species

Confocal Microscopy: Mouse
PMID Dilution Publication
326164701:100Held, R.G., et al. 2020. Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ channels and Ca2+ Entry. Neuron, .
Immunocytochemistry: Mouse
PMID Dilution Publication
244533331:500Etemad, S., et al. 2014. Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.. Journal of Neuroscience, 1446-1461.
199963121:250Obermair, G.J., et al. 2010. Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.. Journal of Biological Chemistry, 5776-5791.
Immunocytochemistry: Rat
PMID Dilution Publication
248095061:1000Scamps, F., et al. 2015. Nerve injury induces a Gem-GTPase-dependent downregulation of P/Q-type Ca2+ channels contributing to neurite plasticity in dorsal root ganglion neurons.. Pflügers Archiv: European Journal of Physiology, 351-366.
Immunohistochemistry: Mouse
PMID Dilution Publication
239488871:500Daschil, N., et al. 2013. CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-β plaques in an Alzheimer''s disease mouse model.. Journal of Alzheimer''s Disease, 439-451.
227379831:250Ferrándiz-Huertas, C., et al. 2013. Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.. Journal of Neurochemistry, 1095-1107.
Immunohistochemistry: Rat
PMID Dilution Publication
205091425ug/mlOrtiz-Miranda, S.I., et al. 2010. Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals.. Journal of Cellular Physiology, 276-288.
Immunoprecipitation: Mouse
PMID Dilution Publication
21228161not listedChen, J., et al. 2011. Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones. Journal of Neuroscience, 512-525.
1902241615ulKlemmer, P., et al. 2009. Proteomics analysis of immuno-precipitated synaptic protein complexes. Journal of Proteomics, 82-90.
Western Blot: Mouse
PMID Dilution Publication
351762211:50Tan, C., et al. 2022. Rebuilding essential active zone functions within a synapse. Neuron, 1-18.
321766881:500Coste de Bagneaux, P., et al. 2020. A homozygous missense variant in CACNB4 encoding the auxiliary calcium channel beta4 subunit causes a severe neurodevelopmental disorder and impairs channel and non-channel functions. PLoS Genetics, e1008625.
307608861:1000Jin, J., et al. 2020. Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior. Molecular Psychiatry, 1035-1049.
314771431:1000Choi, C.S., et al. 2019. Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels. Molecular Brain, 75.
288745221:250Luo, F., et al. 2017. Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L-type Ca2+ channels. PNAS: USA, E8081-E8090.
252092711 : 40Liu, C., et al. 2014. The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons.. Journal of Neuroscience, 12289-12303.
227379831:1000Ferrándiz-Huertas, C., et al. 2013. Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.. Journal of Neurochemistry, 1095-1107.
212418951:250Kaeser, P.S., et al. 2011. RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction.. Cell, 282-295.
Western Blot: Rat
PMID Dilution Publication
221874361:1000Li, L., et al. 2012. Up-regulation of Cavβ3 subunit in primary sensory neurons increases voltage-activated Ca2+ channel activity and nociceptive input in neuropathic pain.. Journal of Biological Chemistry, 6002-6013.
195898631:500Van Gemert, N.G., et al. 2009. Dissociation between rat hippocampal CA1 and dentate gyrus cells in their response to corticosterone: effects on calcium channel protein and current. Endocrinology, 4615-4624.
Western Blot: Swine
PMID Dilution Publication
248483551:1000Tharp, D.L., et al. 2014. Ovariectomy increases L-type Ca(2+) channel activity in porcine coronary smooth muscle. Menopause, 661-668.

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