Anti-Cavbeta4 Ca2+ Channel Antibody FL490 Conjugate (N10/7)

Name: Anti-Cavbeta4 Ca2+ Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-054-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Cavbeta4 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N10/7. It detects human, mouse, pig, and rat Cavbeta4 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Pig, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-054-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Cavbeta4 Ca2+ channel

Target Description

Voltage-dependent L-type calcium channel subunit beta-4 or Cav ß4 is encoded by the gene CACNB4. Cavß4 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß4 is expressed predominantly in the brain (cerebellum) and kidney. Diseases associated with this gene include Episodic Ataxia, Type 5 and Epilepsy.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N10/7

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Cacnb4 Cacnlb4

Molecular Weight

50 kDa

Antigen

Synthetic peptide amino acids 458-474 of rat Cav4 (DENYHNERARKSRNRLS; accession number D4A055)

Species Reactivity

Human, Mouse, Pig, Rat

Antibody Registry ID

AB_2939236

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity against rat Cavβ1b, Cavβ2a, and Cavβ3 in transfected cells

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4)

UniProt Details

UniProt (Human): O00305
UniProt (Immunogen Species): D4A055

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Anti-Cavbeta4 Ca2+ Channel Antibody FL490 Conjugate (N10/7)

SKU: 75-054-FL490

Product Details

Bulk Order Anti-Cavbeta4 Ca2+ Channel Antibody FL490 Conjugate

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