Anti-Cav3.1 Ca2+ Channel Antibody (BSA and Azide free) (N178A/9)

Name: Anti-Cav3.1 Ca2+ Channel Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-206-CF
Price: 486.0 USD
Availability: InStock

Our mouse Cav3.1 Ca2+ channel carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N178A/9. It detects human, mouse, non-human primate, and rat Cav3.1 Ca2+ channel and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Anti-Cav3.1 Ca2+ Channel Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

KO Validated

SKU: 75-206-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Cav3.1 Ca2+ channel

Scientific Background

Voltage-dependent T-type calcium channel subunit alpha or Cav3.1 Ca2+ channel is encoded by the gene CACNA1G. Cav3.1 is a pore forming alpha subunit of T voltage-sensitive calcium channels and gives rise to T-type calcium currents. (transient opening calcium channels). These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav3.1 is expressed in various tissues including heart and smooth muscle, kidney, bone, and brain as a membrane bound protein. Diseases associated with this gene include forms of Spinocerebellar Ataxia

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N178A/9

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Cacna1g

Molecular Weight

>200 kDa

Immunogen

Fusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession number Q9WUT2) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Voltage-dependent T-type calcium channel subunit alpha

UniProt ID

Q9WUT2

Shipping

Shipped on ice packs

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Anti-Cav3.1 Ca2+ Channel Antibody (BSA and Azide free) (N178A/9)

SKU: 75-206-CF

Product Details

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