Voltage-dependent T-type calcium channel subunit alpha or Cav3.1 Ca2+ channel is encoded by the gene CACNA1G. Cav3.1 is a pore forming alpha subunit of T voltage-sensitive calcium channels and gives rise to T-type calcium currents. (transient opening calcium channels). These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav3.1 is expressed in various tissues including heart and smooth muscle, kidney, bone, and brain as a membrane bound protein. Diseases associated with this gene include forms of Spinocerebellar Ataxia
ICC, IHC, WB
Fusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (also known as Voltage-gated/dependent T-type calcium channel alpha-1-G subunit, Cacna1g and NBR13, accession number Q9WUT2); Rat: 96% identity (117/121 amino acids identical); Human: 80% identity (98/122 amino acids identical); 30% identity with Cav3.2
Human, Mouse, Rat
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