Anti-BBS3/Arl6 Antibody (N302/10)

Name: Anti-BBS3/Arl6 Antibody
Brand: NeuroMab
SKU: 75-270
Price: 337.0 USD
Availability: InStock

Our mouse BBS3/Arl6 monoclonal antibody from NeuroMab is produced in-house from clone N302/10. It detects human, mouse, and rat BBS3/Arl6 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Tissue and transfected cell immunoblot: extracts of rat brain membrane (RBM) and COS cells transiently transfected with Flag-tagged BBS3/Arl6 or untagged Kv2.1 plasmid and probed with N302/10 (left) and K89/34 (right) TC supe.

Adult rat brain immunohistochemistry.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-270

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

BBS3/Arl6

Scientific Background

ADP-ribosylation factor-like protein 6, Bardet-Biedl syndrome 3 protein or BBS3/Arl6 is encoded by the gene ARL6 and is a member of the ARF family withing the small GTPase superfamily. BBS3 acts as a regulator of cellular traffic and has roles in protein transport and membrane trafficking. BBS3 is widely expressed in tissues including brain, eye, heart and kidney. Mutations in this gene are associated with Bardet-Biedl syndrome (BBS).

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N302/10

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

ARL6 BBS3

Molecular Weight

20 kDa

Immunogen

Fusion protein amino acids 1-186 (full-length) of human ADP-ribosylation factor-like protein 6 (accession number Q9H0F7) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_11000170

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

ADP-ribosylation factor-like protein 6 (Bardet-Biedl syndrome 3 protein)

UniProt ID

Q9H0F7

Shipping

Shipped on ice packs

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Anti-BBS3/Arl6 Antibody (N302/10)

SKU: 75-270

Product Details

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