Anti-Ankyrin-R/G Antibody Biotin Conjugate (N388A/27)

Name: Anti-Ankyrin-R/G Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-415-BTN
Price: 543.0 USD
Availability: InStock

Our mouse Ankyrin-R/G biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone N388A/27. It detects human, mouse, and rat Ankyrin-R/G and is purified by Protein A chromatography. Works in ELISA, IHC, ICC, WB.

Anti-Ankyrin-R/G Antibody Biotin Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-415-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Ankyrin-R/G

Scientific Background

Ankyrins are scaffold proteins that function to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N388A/27

Isotype

IgG2b

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

ANK1 ANK

Molecular Weight

200 kDa

Immunogen

Fusion Protein Amino acids 1-1881 (full-length) of human Ankyrin-R (accession number P16157) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

Does not cross-react with Ankyrin-BCross-reacts with Ankyrin-G

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

ANK; Ankyrin-1; ANK-1; Ankyrin-R; ankyrin 1; Erythrocyte ankyrin; erythrocytic; SPH2

UniProt ID

P16157
UniProt Summary: Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions.

NCBI Gene ID

286

Shipping

Shipped on ice packs

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Anti-Ankyrin-R/G Antibody Biotin Conjugate (N388A/27)

SKU: 75-415-BTN

Product Details

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