Ankyrins are scaffold proteins that function to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains.
ICC, IHC, WB
Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R (also known as Ankyrin-1, Erythrocyte Ankyrin, ANK-1, ANK and rCG_43073, accession number P16157); Mouse: 90% identity (1678/1858 amino acids identical); Rat: 74% identity (1329/1788 amino acids identical); 50% identity with Ankyrin-B and Ankyrin-G
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with Ankyrin-B
Cross-reacts with Ankyrin-G
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.