Anti-LRRK1 Antibody FL650 Conjugate (N341/12)

Name: Anti-LRRK1 Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-347-FL650
Price: 486.0 USD
Availability: InStock

Our mouse LRRK1 FL650 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N341/12. It detects human and mouse LRRK1 and is purified by Protein A chromatography. KO validated. Works in ICC.

Anti-LRRK1 Antibody FL650 Conjugate

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Species Reactivity

Human, Mouse

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-347-FL650

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

LRRK1

Scientific Background

Leucine Rich Repeat Kinase 1 is encoded by the gene LRRK1. LRRK1 is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, ROCO subfamily. LRRK1 is a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. LRRK1 is thought to play a role in the regulation of bone mass. LRRK1 is overexpressed in lymph node and uterus. Diseases associated with LRRK1 include Osteosclerotic Metaphyseal Dysplasia and Parkinson Disease 3, Autosomal Dominant.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N341/12

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

LRRK1 KIAA1790

Molecular Weight

>200 kDa

Immunogen

Fusion protein amino acids 1695-2015 (C-terminus) of human LRRK1 (accession number Q38SD2) produced recombinantly in E. Coli.

Immunogen Species

Human

Species Reactivity

Human, Mouse

Antibody Registry ID

AB_2940179

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with LRRK2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)

UniProt ID

Q38SD2

Shipping

Shipped on ice packs

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Anti-LRRK1 Antibody FL650 Conjugate (N341/12)

SKU: 75-347-FL650

Product Details

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