Anti-LRRK1 Antibody FL490 Conjugate (N341/12)
Our Anti-LRRK1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N341/12. It is KO validated, detects human and mouse LRRK1, and is purified by Protein A chromatography. It is great for use in ICC.
SKU: 75-347-FL490
Product Details
LRRK1
Leucine Rich Repeat Kinase 1 is encoded by the gene LRRK1. LRRK1 is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, ROCO subfamily. LRRK1 is a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. LRRK1 is thought to play a role in the regulation of bone mass. LRRK1 is overexpressed in lymph node and uterus. Diseases associated with LRRK1 include Osteosclerotic Metaphyseal Dysplasia and Parkinson Disease 3, Autosomal Dominant.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N341/12
IgG1
ICC
Mouse
LRRK1 KIAA1790
>200 kDa
Fusion protein amino acids 1695-2015 (C-terminus) of human LRRK1 (accession number Q38SD2) produced recombinantly in E. Coli.
Human, Mouse
AB_2940176
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
Does not cross-react with LRRK2
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)
UniProt (Human): Q38SD2
UniProt (Immunogen Species): Q38SD2
UniProt (Immunogen Species): Q38SD2