Anti-Clcn5 Antibody FL650 Conjugate (N406/47)

Name: Anti-Clcn5 Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-400-FL650
Price: 486.0 USD
Availability: InStock

Our mouse Clcn5 FL650 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N406/47. It detects human, mouse, and rat Clcn5 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Clcn5 Antibody FL650 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

Biotin

Carrier-Free

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Data Sheet

SKU: 75-400-FL650

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Clcn5

Scientific Background

Chloride Voltage-Gated Channel 5, CLCN5 or H(+)/Cl(-) exchange transporter 5 is encoded by the gene CLCN5 and is a member of the voltage-gated chloride channel (ClC) family. CLCN5 is a proton-coupled chloride transporter. CLCN5 is involved in the acidification of the endosome lumen and is thought to play an important role in renal tubular function. CLCN5 is expressed in kidney, aortic and coronary vascular smooth muscle. Diseases associated with CLCN5 include Dent Disease 1 and X-Linked Recessive Hypophosphatemic Rickets.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N406/47

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Clcn5

Molecular Weight

90 kDa

Immunogen

Fusion protein amino acids 568-746 (C-terminus) of rat Clcn5 (accession number P51796) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940319

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with Clcn4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)

UniProt ID

P51796

Shipping

Shipped on ice packs

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Anti-Clcn5 Antibody FL650 Conjugate (N406/47)

SKU: 75-400-FL650

Product Details

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