Anti-Clcn5 Antibody (N406/47)

Name: Anti-Clcn5 Antibody
Brand: NeuroMab
SKU: 75-400
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N406/47

Applications

ICC, IHC

Host Species

Mouse

Format

Purified

Gene Name

Clcn5

Molecular Weight

90 kDa

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Volume: 100 µL

Variant

Price:

$295

Quantity:

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Product Details

Target

H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)

Target Description

Chloride Voltage-Gated Channel 5, CLCN5 or H(+)/Cl(-) exchange transporter 5 is encoded by the gene CLCN5 and is a member of the voltage-gated chloride channel (ClC) family. CLCN5 is a proton-coupled chloride transporter. CLCN5 is involved in the acidification of the endosome lumen and is thought to play an important role in renal tubular function. CLCN5 is expressed in kidney, aortic and coronary vascular smooth muscle. Diseases associated with CLCN5 include Dent Disease 1 and X-Linked Recessive Hypophosphatemic Rickets.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N406/47

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Clcn5

Molecular Weight

90 kDa

Antigen

Fusion protein amino acids 568-746 (C-terminus) of rat Clcn5 (also known as H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, Chloride transporter ClC-5, Clc5 and CLCK2, accession number P51796); Mouse: 99% identity (178/179 amino acids identical); Human: 98% identity (177/179 amino acids identical); 70% identity with Clcn3 and Clcn4

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2491083

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with Clcn4

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)

UniProt Details

UniProt (Human): P51795
UniProt (Immunogen Species): P51796

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Anti-Clcn5 Antibody (N406/47)

Anti-Clcn5 Antibody
SKU: 75-400

Bulk Order Anti-Clcn5 Antibody

Product Details

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Anti-Clcn5 Antibody (N406/47)

Anti-Clcn5 Antibody SKU: 75-400

Bulk Order Anti-Clcn5 Antibody

Product Details

Anti-Clcn5 Antibody
SKU: 75-400