Anti-Clcn5 Antibody (N406/47)

Name: Anti-Clcn5 Antibody
Brand: NeuroMab
SKU: 75-400
Price: 319.0 USD
Availability: InStock

Our Anti-Clcn5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N406/47. It detects human, mouse, and rat Clcn5, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-400

Volume: 100 µL

Variant

Price:

$319

Quantity:

Product Details

Target

Clcn5

Target Description

Chloride Voltage-Gated Channel 5, CLCN5 or H(+)/Cl(-) exchange transporter 5 is encoded by the gene CLCN5 and is a member of the voltage-gated chloride channel (ClC) family. CLCN5 is a proton-coupled chloride transporter. CLCN5 is involved in the acidification of the endosome lumen and is thought to play an important role in renal tubular function. CLCN5 is expressed in kidney, aortic and coronary vascular smooth muscle. Diseases associated with CLCN5 include Dent Disease 1 and X-Linked Recessive Hypophosphatemic Rickets.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N406/47

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Clcn5

Molecular Weight

90 kDa

Antigen

Fusion protein amino acids 568-746 (C-terminus) of rat Clcn5 (accession number P51796) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2491083

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Clcn4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)

UniProt Details

UniProt (Human): P51795
UniProt (Immunogen Species): P51796

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Anti-Clcn5 Antibody (N406/47)

SKU: 75-400

Product Details

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