Anti-CASK Antibody (BSA and Azide free) (K56A/50)

Name: Anti-CASK Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-000-CF
Price: 486.0 USD
Availability: InStock

Our mouse CASK carrier-free monoclonal antibody from NeuroMab is produced in-house from clone K56A/50. It detects chicken, human, mouse, non-human primate, rat, Xenopus, and zebrafish CASK and is purified by Protein A chromatography. KO validated. Works in WB, IHC, ICC, ELISA.

Anti-CASK Antibody (BSA and Azide free)

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Species Reactivity

Chicken, Frog, Human, Mouse, Non-Human Primate, Rat, Xenopus, Zebrafish

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

KO Validated

SKU: 75-000-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

CASK

Scientific Background

Calcium/Calmodulin-Dependent Serine Protein Kinase or CASK scaffolding protein is encoded by the gene CASK. CASK is a member of the MAGUK (membrane-associated guanylate kinase) protein family. CASK is a a calcium/calmodulin-dependent serine protein kinase. CASK is found in many different tissues including kidney, lung, liver and brain. In the brain, CASK protein is located at synapses. CASK acts as a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Mutations in this gene are associated with FG syndrome 4, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

K56A/50

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

CASK LIN2

Molecular Weight

100 kDa

Immunogen

Fusion protein amino acids 318-415 of human CASK/Lin2 (accession number Q62915) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Chicken, Frog, Human, Mouse, Non-Human Primate, Rat, Xenopus, Zebrafish

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)

UniProt ID

O14936

Shipping

Shipped on ice packs

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Anti-CASK Antibody (BSA and Azide free) (K56A/50)

SKU: 75-000-CF

Product Details

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