Calcium/Calmodulin-Dependent Serine Protein Kinase or CASK scaffolding protein is encoded by the gene CASK. CASK is a member of the MAGUK (membrane-associated guanylate kinase) protein family. CASK is a a calcium/calmodulin-dependent serine protein kinase. CASK is found in many different tissues including kidney, lung, liver and brain. In the brain, CASK protein is located at synapses. CASK acts as a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Mutations in this gene are associated with FG syndrome 4, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability.
IHC, IP, WB
Fusion protein amino acids 318-415 of rat CASK/Lin2 (accession number Q62915); Human: 100% identity; Mouse=100% identity
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No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Peripheral plasma membrane protein CASK (hCASK) (EC 18.104.22.168) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)