Anti-Ankyrin-R Antibody FL490 Conjugate (N388A/10)

Name: Anti-Ankyrin-R Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-380-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Ankyrin-R FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N388A/10. It detects human, mouse, and rat Ankyrin-R and is purified by Protein A chromatography. KO validated. Works in IHC, ICC.

Anti-Ankyrin-R Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-380-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Ankyrin-R

Scientific Background

Ankyrin-1 or -Ankyrin-R is encoded by the gene ANK1. Ankyrin R is a scaffold protein that functions to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin R is found expressed in erythrocytes, skeletal muscle and brain. Diseases associated with this gene include Spherocytosis.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N388A/10

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ANK1 ANK

Molecular Weight

200 kDa

Immunogen

Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R (accession number P16157) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940264

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Ankyrin-B or Ankyrin-G

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin)

UniProt ID

P16157

Shipping

Shipped on ice packs

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Anti-Ankyrin-R Antibody FL490 Conjugate (N388A/10)

SKU: 75-380-FL490

Product Details

Bulk Order Anti-Ankyrin-R Antibody FL490 Conjugate

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