Anti-Ankyrin-R Antibody FL650 Conjugate (N388A/10)

Name: Anti-Ankyrin-R Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-380-FL650
Price: 474.0 USD
Availability: InStock

Our Anti-Ankyrin-R mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N388A/10. It is KO validated, detects human, mouse, and rat Ankyrin-R, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-380-FL650

Volume: 200 µL

Variant

Price:

$474.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Ankyrin-R

Target Description

Ankyrin-1 or -Ankyrin-R is encoded by the gene ANK1. Ankyrin R is a scaffold protein that functions to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin R is found expressed in erythrocytes, skeletal muscle and brain. Diseases associated with this gene include Spherocytosis.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N388A/10

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ANK1 ANK

Molecular Weight

200 kDa

Antigen

Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R (accession number P16157) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940267

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with Ankyrin-B or Ankyrin-G

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin)

UniProt ID

P16157

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Anti-Ankyrin-R Antibody FL650 Conjugate (N388A/10)

SKU: 75-380-FL650

Product Details

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