Anti-TrpC1 Antibody (1F1)

Name: Anti-TrpC1 Antibody
Brand: NeuroMab
SKU: 75-278
Price: 337.0 USD
Availability: InStock

Our mouse TrpC1 monoclonal antibody from NeuroMab is produced in-house from clone 1F1. It detects human, mouse, and rat TrpC1 and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Adult rat brain membrane immunoblot

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-278

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

TrpC1

Scientific Background

Short transient receptor potential channel 1 or TrpC1 is encoded by the gene TRPC1.TrpC1 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. TrpC1 expression seems to be ubiquitous, and is widely expressed in throughout the brain.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

1F1

Isotype

IgG1

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

TRPC1 TRP1

Molecular Weight

80-90 kDa

Immunogen

Fusion protein amino acids 27-306 (cytoplasmic N-terminus) of human TRPC1 (accession number P48995) produced recombinantly in E. Coli.

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2315951

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with TRPC4 (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

HTRP-1; Short transient receptor potential channel 1; TrpC1; TRP-1; Transient receptor protein 1; capacitative calcium channel protein Trp1; transient receptor potential canonical 1

UniProt ID

P48995
UniProt Summary: Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions.

NCBI Gene ID

7220

Shipping

Shipped on ice packs

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Anti-TrpC1 Antibody (1F1)

SKU: 75-278

Product Details

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