Anti-Thorase/Atad1 Antibody FL594 Conjugate (N125/10)

Name: Anti-Thorase/Atad1 Antibody FL594 Conjugate
Brand: NeuroMab
SKU: 75-157-FL594
Price: 486.0 USD
Availability: InStock

Our mouse Thorase/Atad1 FL594 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N125/10. It detects human, mouse, and rat Thorase/Atad1 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Thorase/Atad1 Antibody FL594 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-157-FL594

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Thorase/Atad1

Scientific Background

ATPase Family AAA Domain-containing 1 is encoded by the gene ATAD1. ATAD1 plays a critical role in regulating the surface expression of AMPA receptors thereby regulating synaptic plasticity, learning, and memory. Diseases associated with ATAD1 include Hyperekplexia 4 and Hyperekplexia.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N125/10

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Atad1

Molecular Weight

40 kDa

Immunogen

Fusion protein amino acids 1-361 (full-length) of mouse Thorase (accession number Q9D5T0) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939582

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

4921525H23Rik; ATPase family AAA domain-containing protein 1; Thorase; EC 3.6.1.3

UniProt ID

Q9D5T0
UniProt Summary: Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria. Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane. Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.

NCBI Gene ID

67979

Shipping

Shipped on ice packs

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Anti-Thorase/Atad1 Antibody FL594 Conjugate (N125/10)

SKU: 75-157-FL594

Product Details

Bulk Order Anti-Thorase/Atad1 Antibody FL594 Conjugate

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