Anti-SynDIG4 Antibody (L102/45)

Name: Anti-SynDIG4 Antibody
Brand: NeuroMab
SKU: 75-409
Price: 337.0 USD
Availability: InStock

Our mouse SynDIG4 monoclonal antibody from NeuroMab is produced in-house from clone L102/45. It detects human, mouse, and rat SynDIG4 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Adult rat hippocampus immunohistochemistry.

Adult rat hippocampus immunohistochemistry.

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-409

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

SynDIG4

Scientific Background

Proline Rich Transmembrane Protein 1 is encoded by the gene PRRT1. PRRT1 is a member of the CD225/Dispanin family. PRRT1 is expressed in the brain. Diseases associated with PRRT1 include Tinea Capitis.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L102/45

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Prrt1 Ng5

Molecular Weight

40 kDa

Immunogen

Fusion protein amino acids 1-66 (extracellular N-terminus) of rat SynDIG4 (accession number Q6MG82) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2531894

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

DSPD1; Proline-rich transmembrane protein 1; Orf31; Dispanin subfamily D member 1

UniProt ID

Q6MG82
UniProt Summary: Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression.

NCBI Gene ID

406167

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Anti-SynDIG4 Antibody (L102/45)

SKU: 75-409

Product Details

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