Anti-Aldh1L1 (Staining) Antibody (N103/31)

Name: Anti-Aldh1L1 (Staining) Antibody
Brand: NeuroMab
SKU: 75-164
Price: 337.0 USD
Availability: InStock

Our mouse Aldh1L1 (staining) monoclonal antibody from NeuroMab is produced in-house from clone N103/31. It detects human, mouse, and rat Aldh1L1 (staining) and is purified by Protein A chromatography. Works in IHC, ICC, ELISA.

Adult rat hippocampus immunohistochemistry.

Adult rat cortex immunofluorescence. Images courtesy of Lynette Foo and Dr. Ben Barres, Stanford University.

Cerebellum immunofluorescence. Images courtesy of Lynette Foo and Dr. Ben Barres, Stanford University.

Adult rat hippocampus immunohistochemistry.

Click on image to zoom

Species Reactivity

Human, Rat

Applications

ELISA, ICC, IHC

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

Trial Size

SKU: 75-164

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Aldh1L1 (staining)

Scientific Background

Aldehyde dehydrogenase family 1 member L1 (Aldh1L1) is a member of the aldehyde dehydrogenase family. This protein is an enzyme that catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. It is an astrocyte marker and also is expressed in the liver. It is proposed to play a role in regulation of cellular THF levels and inhibiting cell proliferation. Alterations in Aldh1L1 have been implicated in Congenital Hydrocephalus

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N103/31

Isotype

IgG1

Applications

ELISA, ICC, IHC

Host Species

Mouse

Gene Name

Aldh1l1 Fthfd

Molecular Weight

100 kDa

Immunogen

Protein amino acids 1-902 (full-length) of rat Aldh1L1 (accession number P28037) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Rat

Antibody Registry ID

AB_10671695

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.90

Dilution Ranges

WB: 1:2000
IHC: 1:250
ICC: 1:250

Conjugate

Unconjugated

Specificity

No cross-reactivity against Aldh1L2

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

FDH; Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; 10-formyltetrahydrofolate dehydrogenase; EC 1.5.1.6; FBP-CI; Aldehyde dehydrogenase family 1 member L1; formyltetrahydrofolate dehydrogenase

UniProt ID

P28037
UniProt Summary: Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide. May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde.

NCBI Gene ID

64392

Shipping

Shipped on ice packs

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Anti-Aldh1L1 (Staining) Antibody (N103/31)

SKU: 75-164

Product Details

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