Anti-Navbeta3 Na+ Channel Antibody (BSA and Azide free) (N396/29)

Name: Anti-Navbeta3 Na+ Channel Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-391-CF
Price: 486.0 USD
Availability: InStock

Our mouse Navbeta3 Na+ channel carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N396/29. It detects mouse and rat Navbeta3 Na+ channel and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Anti-Navbeta3 Na+ Channel Antibody (BSA and Azide free)

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Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

SKU: 75-391-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Navbeta3 Na+ channel

Scientific Background

Sodium channel subunit beta-3 or Navbeta3 Na+ channel is encoded by SCN3B. Voltage gated sodium channels are made up of an alpha (pore forming) subunit and 1 or 2 beta subunits. Navß3 is a transmembrane protein and acts as a regulatory subunit in excitable membranes and modulates the kinetics of channel. Nabß3 is expressed in many tissues, including the central and peripheral nervous system, heart and pancreatic endocrine cells. Diseases associated with SCN3A include forms of Epilepsy and Encephalopathy.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N396/29

Isotype

IgG2b

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Scn3b

Molecular Weight

40 kDa

Immunogen

Fusion protein amino acids 1-215 (full-length) of rat Navbeta3 (accession number Q9JK00) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Does not cross-react with Navbeta1, Navbeta2 or Navbeta4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Sodium channel subunit beta-3

UniProt ID

Q9JK00

Shipping

Shipped on ice packs

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Anti-Navbeta3 Na+ Channel Antibody (BSA and Azide free) (N396/29)

SKU: 75-391-CF

Product Details

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