Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate (N396/29)

Name: Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate
Brand: NeuroMab
SKU: 75-391-FL594
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

Unconjugated

490

550

650

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N396/29

Applications

ICC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Scn3b

Molecular Weight

40 kDa

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Volume: 200 µL

Variant

Price:

$445

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Product Details

Target

Navbeta3 Na+ channel

Target Description

Sodium channel subunit beta-3 or Navbeta3 Na+ channel is encoded by SCN3B. Voltage gated sodium channels are made up of an alpha (pore forming) subunit and 1 or 2 beta subunits. Navß3 is a transmembrane protein and acts as a regulatory subunit in excitable membranes and modulates the kinetics of channel. Nabß3 is expressed in many tissues, including the central and peripheral nervous system, heart and pancreatic endocrine cells. Diseases associated with SCN3A include forms of Epilepsy and Encephalopathy.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N396/29

Isotype

IgG2b

Applications

ICC

Host Species

Mouse

Gene Name

Scn3b

Molecular Weight

40 kDa

Antigen

Fusion protein amino acids 1-215 (full-length) of rat Navbeta3 (accession number Q9JK00) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940286

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

Specificity

Does not cross-react with Navbeta1, Navbeta2 or Navbeta4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Sodium channel subunit beta-3

UniProt Details

UniProt (Human): Q9NY72
UniProt (Immunogen Species): Q9JK00

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Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate (N396/29)

Available Conjugates

Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate
SKU: 75-391-FL594

Bulk Order Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate

Product Details

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Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate (N396/29)

Available Conjugates

Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate SKU: 75-391-FL594

Bulk Order Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate

Product Details

Anti-Navbeta3 Na+ Channel Antibody FL594 Conjugate
SKU: 75-391-FL594