Anti-Mortalin/GRP75 Antibody FL490 Conjugate (N52A/42)

Name: Anti-Mortalin/GRP75 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-127-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Mortalin/GRP75 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N52A/42. It detects C. elegans, human, mouse, non-human primate, and rat Mortalin/GRP75 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Mortalin/GRP75 Antibody FL490 Conjugate

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Species Reactivity

C. elegans, Human, Mouse, Non-Human Primate, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-127-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Mortalin/GRP75

Scientific Background

Mitochondrial stress-70 protein or Mortalin/GRP75 is encoded by the gene HSPA9. Mortalin is a chaperone protein and plays a role in cell proliferation, stress response and mitochondria maintenance. It is widely expressed in tissues in mitochondria, endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. Diseases associated with this gene include Even-Plus Syndrome and Sideroblastic Anemia 4.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N52A/42

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Hspa9 Grp75 Hsp74 Hspa9a

Molecular Weight

75 kDa

Immunogen

Identified as off-target mAb in screen for anti-Salm2 NeuroMabs (immunogen was fusion protein amino acids 551-766 of mouse SALM2). Target identified as Mortalin/Grp75 by LC-MS/MS analysis of protein immunopurified from rat brain using N52A/42.

Immunogen Species

Mouse

Species Reactivity

C. elegans, Human, Mouse, Non-Human Primate, Rat

Antibody Registry ID

AB_2939472

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (Peptide-binding protein 74) (PBP74) (p66 MOT)

UniProt ID

P38647

Shipping

Shipped on ice packs

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Anti-Mortalin/GRP75 Antibody FL490 Conjugate (N52A/42)

SKU: 75-127-FL490

Product Details

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